| Type | Description |
|---|---|
| Definition | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:33:00 | CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis. | 32549410 |
| 2020-12-12 13:28:00 | Heritable genetic background alters survival and phenotype of Mll-AF9-induced leukemias. | 32768438 |
| 2017-10-28 13:15:00 | Atg5-dependent autophagy contributes to the development of acute myeloid leukemia in an MLL-AF9-driven mouse model. | 27607576 |
| 2017-08-05 11:18:00 | YEATS domain of AF9 directly links histone crotonylation to active transcription. | 27105114 |
| 2016-10-22 10:54:00 | Data suggest that RAS-homolog enriched in brain protein (Rheb1) promotes MLL-AF9 fusion protein initiated acute myeloid leukemia (AML) progression through target of rapamycin complex 1 (mTORC1) signaling pathway. | 27071307 |
| Type | IDs |
|---|---|
| Synonymous | 2210011H10Rik, 2610012I03Rik, 3830408D16Rik, Af9, D4Ertd321e |
| Gene |
UniProtKB-ID:
AF9_MOUSE,
Q9D2P1_MOUSE,
Q3UIA3_MOUSE
UniprotKB:
A2AM29,
Q9D2P1,
Q3UIA3
UniParc:
UPI0000022EE1,
UPI0000022EE0,
UPI00001F0FA2
EMBL:
AL929429,
AK147009,
AL806533,
AL831756,
AK019458,
AF333960,
BC021420,
AL929524
Ensembl:
ENSMUSG00000028496
KO:
mmu:70122
|
| Nucleutide sequences |
EMBL-CDS:
AAK28536.1,
AAH21420.1,
BAB31731.1,
BAE27603.1
Ensembl_TRS:
ENSMUST00000078090,
ENSMUST00000126353,
ENSMUST00000149357
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077232,
ENSMUSP00000129523,
ENSMUSP00000128366
RefSeq:
XP_036020305.1,
XP_030109631.1,
NP_084207.2,
NP_001273087.1,
NP_081602.3,
XP_030109633.1,
XP_030109632.1,
XP_036020304.1,
XP_006538313.1,
XP_006538316.1
|
| Others |
UniRef100:
UniRef100_Q9D2P1,
UniRef100_A2AM29,
UniRef100_Q3UIA3
UniRef90:
UniRef90_P42568,
UniRef90_Q9D2P1,
UniRef90_Q3UIA3
UniRef50:
UniRef50_A0A2I0LRM4,
UniRef50_P42568,
UniRef50_Q9D2P1
UniGene:
Mm.288898,
Mm.472285
CCDS:
CCDS38796.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员