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701 BUB1B

701

BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

protein-coding

Homo sapiens

基因描述

Type Description
Definition BUB1 mitotic checkpoint serine/threonine kinase B

研究结论

Date Results Publications
2021-04-17 13:15:00 BUB1B Overexpression Is an Independent Prognostic Marker and Associated with CD44, p53, and PD-L1 in Renal Cell Carcinoma. 33588420
2021-02-20 13:36:00 Discovery of Novel Agents on Spindle Assembly Checkpoint to Sensitize Vinorelbine-Induced Mitotic Against Human Non-Small Cell Lung Cancers. 32764382
2020-06-06 13:18:00 Downregulation of Mad2 and BubR1 increase the malignant behavior and nocodazole resistance of SiHa cells via causing spindle assembly checkpoint defect. 31523901
2020-02-08 11:38:00 the ependymal cell layer does not form in the conditional knockout, revealing an unrecognized role of BubR1 in assuring the integrity of the ventricular system, which may account for the presence of hydrocephalus in some patients. 30668728
2020-02-01 11:46:00 The up-regulation of BUB1B, CCNA2, CDC20, CDK1, and WEE1 in tumor tissues are associated with worse overall survival and disease-free survival in pancreatic ductal adenocarcinoma and is correlated with advanced tumor stage and tumor development. 30765611

名称对应

Type IDs
Synonymous BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1
Gene
UniProtKB-ID: BUB1B_HUMAN
UniprotKB: O60566
UniParc: UPI000006E699, UPI000192C264, UPI000192C265
EMBL: AF046079, AF310214, AF310197, AF310192, AF310205, AF310195, AK312709, AK296795, AF310209, AF310200, AF310202, AF310210, AF310204, AF310199, AF310203, AF310208, AF068760, AF310213, AF310211, AF310201, AF310196, AF310207, BC018739, AF310194, AF310206, AF310198, AF310193, AF053306, AF035933, AB208782, AK296984, AF310212, AF107297, AF046918
Ensembl: ENSG00000156970
KO: hsa:701
Nucleutide sequences
EMBL-CDS: BAG59371.1, AAD11941.1, AAH18739.1, AAC33435.1, AAL10712.1, AAC19118.1, BAG35587.1, AAC23736.1, AAC06260.1, AAC12730.2, BAG59525.1, BAD92019.1
Ensembl_TRS: ENST00000412359, ENST00000287598
Protein sequencees
Ensembl_PRO: ENSP00000287598, ENSP00000398470
RefSeq: NP_001202.5
Others
UniRef100: UniRef100_O60566
UniRef90: UniRef90_O60566
UniRef50: UniRef50_O60566
UniGene: Hs.513645
CCDS: CCDS10053.1

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