Vkorc1l1 - vitamin K epoxide reductase complex, subunit 1-like 1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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69568 Vkorc1l1

基因描述

Type	Description
Definition	vitamin K epoxide reductase complex, subunit 1-like 1

研究结论

Date	Results	Publications
2019-10-26 12:43:00	VKORC1L1 supports vitamin K-dependent (VKD) protein protein carboxylation in vivo.	29321368
2019-09-28 12:02:00	Vkorc1l1 promotes adipogenesis and possibly obesity. Downregulation of Vkorc1l1 increases intracellular vitamin K2 level and impedes preadipocyte differentiation.	29963761
2016-04-23 10:04:00	quantified mRNA levels for VKORC1, VKORC1L1, GGCX, and NQO1 and measured VKOR enzymatic activities in 29 different tissues	25747820
2013-12-07 11:27:00	The involvement of VKORC1L1 in VKOR activity partly explains the low susceptibility of some extrahepatic tissues to vitamin K antagonists.	23928358
2010-01-21 00:00:00	molecular cloning	14765194

名称对应

Type	IDs
Synonymous	2310024K08Rik
Gene	UniProtKB-ID: VKORL_MOUSE, Q0VGU5_MOUSE, A0A0M3HEP8_MOUSE UniprotKB: Q6TEK5, Q0VGU5, A0A0M3HEP8 UniParc: UPI00001C35EF, UPI0000473D3D, UPI00001F2B8B EMBL: BC085133, BC138132, AY423046, BC125315, AC164071, AC161345 Ensembl: ENSMUSG00000066735 KO: mmu:69568
Nucleutide sequences	EMBL-CDS: AAI38133.1, AAI25316.1, AAR82916.1, AAH85133.1 Ensembl_TRS: ENSMUST00000051758, ENSMUST00000201855, ENSMUST00000073945
Protein sequencees	Ensembl_PRO: ENSMUSP00000059139, ENSMUSP00000144608, ENSMUSP00000073601 RefSeq: NP_001001327.1, NP_081397.1, NP_001273311.1
Others	UniRef100: UniRef100_Q0VGU5, UniRef100_A0A0M3HEP8, UniRef100_Q6TEK5 UniRef90: UniRef90_A0A0M3HEP8, UniRef90_Q0VGU5, UniRef90_Q6TEK5 UniRef50: UniRef50_Q0VGU5, UniRef50_Q6TEK5, UniRef50_A0A141MJA4 UniGene: Mm.288718 CCDS: CCDS19703.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
29963761	The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice. Obesity (Silver Spring) Yi Ding , Jing Cui , Qi Wang , Suqin Shen , Tian Xu , Huiru Tang , Min Han , Xiaohui Wu	2018-08-01	-
29321368	VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight Julie Lacombe , Mark A Rishavy , Kathleen L Berkner , Mathieu Ferron	2018-01-11	-
25747820	Two enzymes catalyze vitamin K 2,3-epoxide reductase activity in mouse: VKORC1 is highly expressed in exocrine tissues while VKORC1L1 is highly expressed in brain. Thromb. Res. Michael Caspers , Katrin J Czogalla , Kerstin Liphardt , Jens MÃ¼ller , Philipp Westhofen , Matthias Watzka , Johannes Oldenburg	2015-05-01	Vkorc1, Vkorc1l1
25753038	GGCX and VKORC1 inhibit osteocalcin endocrine functions. J. Cell Biol. Mathieu Ferron , Julie Lacombe , AmÃ©lie Germain , Franck Oury , GÃ©rard Karsenty	2015-03-16	Bglap, Vkorc1, Ggcx
23928358	VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy. J Biol Chem Abdessalem Hammed , Benjamin Matagrin , Gabriele Spohn , Caroline Prouillac , Etienne Benoit , Virginie Lattard	2013-10-04	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11
16778019	Characterization of the piRNA complex from rat testes. Science Nelson C Lau , Anita G Seto , Jinkuk Kim , Satomi Kuramochi-Miyagawa , Toru Nakano , David P Bartel , Robert E Kingston	2006-07-21	Gm10505, Gm20204, Gm10619, Gm21221, Gm21269, Gm21284, Gm21388, Enkd1, LOC102632156, Gm30511, Gm14144, Gm30936, Gm31138, Gm31181, Gm32994, Gm33319, Gm11802, Gm33898, LOC102637737, Gm34856, Gm36617, Gm36877, Gm14244, Kdm3a, Ccdc117, Gm41109, Scrib, Unc119b, Mgat5, Prkab2, Rcc2, Abl2, Alas1, Ankfy1, Birc2, Cbl, Cbx5, Cebpg, Crkl, Cux1, Elk4, Pofut1, Usp15, Lancl1, Gml2, Mlc1, Glmn, Mcl1, Nfatc3, Pafah1b2, Npepps, Rad51d, Rps15, Shc1, Spin1, Strbp, Aph1b, Stxbp4, Tmem194, Lcor, Kctd7, Gabpb2, Nudt15, Slc43a2, Dnajc27, Wdr41, Hmbox1, Dedd, Nr2c2, Tgoln1, Tub, Tuba3b, Zbtb10, Otud7b, Gba2, Crebl2, Ddx19b, Cdk10, Map2k5, Mgll, Ago2, Sec31b, Dcaf10, Sbno1, Rpgrip1l, Arhgap20, Zc3h12c, Ccdc15, Fktn, Clcn6, Gins2, Dnajb9, Tbl2, Ip6k1, Tacc1, C530008M17Rik, Kctd10, 9330102E08Rik, Zc3h4

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