| Type | Description |
|---|---|
| Definition | membrane-associated ring finger (C3HC4) 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:20:00 | MITOL dysfunction causes dwarfism with anterior pituitary hypoplasia. | 32302394 |
| 2020-01-18 12:08:00 | Results showed that mitochondrial abnormalities in MITOL KO brain induced mild behavioral changes. MITOL KO brain also displayed enhanced oxidative stress, which may result from increased electron leakage from mitochondria. The reduced ER-mitochondria tethering and excessive mitochondrial fission may trigger neuroinflammation through oxidative stress. | 31416892 |
| 2019-11-23 11:18:00 | MARCH5 is regulated by peroxisome proliferator-activated receptor-gamma (PPARgamma) during adipogenesis and is correlated with fat mass across a panel of genetically diverse mouse strains, in ob/ob mice, and in humans. Furthermore, manipulation of MARCH5 expression in vitro and in vivo alters mitochondrial function, affects cellular metabolism, and leads to differential regulation of several metabolic genes | 30512991 |
| 2017-07-15 12:11:00 | These findings suggest that MITOL plays a protective role against apoptosis in cardiomyocytes. | 27444773 |
| 2016-05-14 12:18:00 | MARCH5 binds MAVS only during viral stimulation when MAVS forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS. | 26246171 |
| Type | IDs |
|---|---|
| Synonymous | 1810015H18Rik, 2310008I22Rik, 2700055A20Rik, 5730499H23Rik, E130202O05Rik, MARCH-V, MITOL, Marchv, Rnf153 |
| Gene |
UniProtKB-ID:
MARH5_MOUSE,
A2RTC8_MOUSE,
A0A0R4J1H0_MOUSE
UniprotKB:
Q3KNM2,
A2RTC8,
A0A0R4J1H0
UniParc:
UPI0000029902,
UPI000006D0BC
EMBL:
BC064752,
BC107215,
BC132455,
AK003478,
AK009232,
BC132457,
AC161238
Ensembl:
ENSMUSG00000023307,
ENSMUSG00000111123
KO:
mmu:69104
|
| Nucleutide sequences |
EMBL-CDS:
AAI07216.1,
BAB26154.1,
BAB22809.1,
AAH64752.1,
AAI32456.1,
AAI32458.1
Ensembl_TRS:
ENSMUST00000215066,
ENSMUST00000024078,
ENSMUST00000112391
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000150553,
ENSMUSP00000024078,
ENSMUSP00000108010
RefSeq:
NP_001365727.1,
NP_001157809.1,
NP_081590.3,
NP_001365726.1,
NP_001157808.1
|
| Others |
UniRef100:
UniRef100_A0A0R4J1H0,
UniRef100_Q9NX47
UniRef90:
UniRef90_Q9NX47,
UniRef90_A0A2K6MDF3
UniRef50:
UniRef50_A0A2K6MDF3,
UniRef50_Q9NX47
UniGene:
Mm.175989
CCDS:
CCDS29776.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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