| Type | Description |
|---|---|
| Definition | serine and arginine rich splicing factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 12:23:00 | SRSF1 promotes vascular smooth muscle cell (VSMC) proliferation and injury-induced neointima formation. SRSF1 favors the induction of a truncated p53 isoform, Delta133p53, which has an equal proliferative effect and in turn transcriptionally activates Kruppel-like factor 5 (KLF5) via the Delta133p53-EGR1 complex, resulting in an accelerated cell-cycle progression and increased VSMC proliferation. | 28799539 |
| 2018-11-10 12:00:00 | present results suggested that pathologically high cyclic stretch induces the shuttling of SRSF1 which results in the secretive pattern splicing of VEGFA and finally contributes to the proliferation of vascular smooth muscle cells. | 29974845 |
| 2013-07-06 11:19:00 | a new mechanism of posttranscriptional regulation of DIO1 and show deregulation of DIO1 expression in pituitary adenoma, possibly resulting from disturbed expression of SF2/ASF. | 23462647 |
| Type | IDs |
|---|---|
| Synonymous | Sfrs1 |
| Gene |
UniProtKB-ID:
D4A9L2_RAT
UniprotKB:
D4A9L2
UniParc:
UPI0000001220
EMBL:
CH473948,
AABR07030193
Ensembl:
ENSRNOG00000050323
KO:
rno:689890
|
| Nucleutide sequences |
EMBL-CDS:
EDM05624.1
Gene_ORFName:
rCG_34610
Ensembl_TRS:
ENSRNOT00000073005
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000064933
RefSeq:
NP_001103022.1,
XP_008766336.1
|
| Others |
UniRef100:
UniRef100_Q07955
UniRef90:
UniRef90_Q07955
UniRef50:
UniRef50_Q07955
UniGene:
Rn.84878
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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