| Type | Description |
|---|---|
| Definition | pre-mRNA processing factor 31 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:46:00 | In a mouse model containing the p.A216P mutation in Prpf31, study found mislocalization and aggregation of the mutant Prpf31 protein with concomitant depletion of normal protein. These results indicate mixed haploinsufficiency and dominant negative mechanisms involved in retinal degeneration due to mutations in PRPF31. | 31892304 |
| 2020-02-08 11:37:00 | major retinal pigment epithelium defects were identified in Prpf31-mutant mice | 31884616 |
| 2016-05-07 10:43:00 | The mouse retinal pigment epithelium (RPE)is the primary cell affected by mutations in the RNA splicing factors (PRPF3, PRPF8, and PRPF31), and these changes occur at an early age. | 25111227 |
| 2011-08-06 10:37:00 | found that PRP31 and PRPC8 as well as snRNAs are highly expressed in retinal cells | 21283520 |
| 2011-07-16 10:50:00 | CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31 | 21385873 |
| Type | IDs |
|---|---|
| Synonymous | 1500019O16Rik, 2810404O06Rik, AW554706, PRP31, RP11 |
| Gene |
UniProtKB-ID:
PRP31_MOUSE
UniprotKB:
Q8CCF0
UniParc:
UPI00003575DB,
UPI0006B2D8CC,
UPI0000021093
EMBL:
CT010189,
AK051260,
AK044398,
AK033190,
AC130680,
AK044457,
AK033283,
AY040823,
BC057877,
AK005294,
BC018376,
BC061461
Ensembl:
ENSMUSG00000008373
KO:
mmu:68988
|
| Nucleutide sequences |
EMBL-CDS:
BAC34578.1,
AAK77987.1,
BAC25109.1,
CAJ18397.1,
AAH57877.1,
BAC31931.1,
BAC28220.1,
AAH61461.1,
BAC28192.1,
BAC31903.1,
AAH18376.1
Ensembl_TRS:
ENSMUST00000125782,
ENSMUST00000179769,
ENSMUST00000108636,
ENSMUST00000008517
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000136031,
ENSMUSP00000146017,
ENSMUSP00000104276,
ENSMUSP00000008517
RefSeq:
NP_001153186.1,
NP_081604.3
|
| Others |
UniRef100:
UniRef100_Q8CCF0
UniRef90:
UniRef90_Q8WWY3
UniRef50:
UniRef50_Q8WWY3
UniGene:
Mm.246863
CCDS:
CCDS39729.1,
CCDS51965.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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