| Type | Description |
|---|---|
| Definition | transmembrane and coiled-coil domains 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 11:30:00 | The role of TMCO1 in regulating lipid-metabolism and mitochondrial function. | 30929916 |
| 2019-09-14 12:55:00 | Tmco1 is required for ovarian follicle development, which is closely linked with the role of TMCO1 in maintaining normal ER Ca2+ store in GCs. Deletion of Tmco1 can cause ER Ca2+ overloaded in GCs followed by ER stress and oxidative stress. | 29467381 |
| 2019-04-27 10:32:00 | An essential role of TMCO1 in osteogenesis mediated by local Ca(2+)/CaMKII signaling in osteoblasts. | 30962442 |
| 2016-12-17 10:11:00 | TMCO1 provides a protective mechanism to prevent overfilling of endoplasmic reticulum stores with Ca(2+) ions | 27212239 |
| Type | IDs |
|---|---|
| Synonymous | 1190006A08Rik, 4930403O06Rik, AA109065, AU022572, ESTM39 |
| Gene |
UniProtKB-ID:
TMCO1_MOUSE,
Q3V4A0_MOUSE
UniprotKB:
Q921L3,
Q3V4A0
UniParc:
UPI0000022931,
UPI000052CD17
EMBL:
BC019761,
BC020098,
AK162344,
AK037709,
BC011457,
AK004504
Ensembl:
ENSMUSG00000052428
KO:
mmu:68944
|
| Nucleutide sequences |
EMBL-CDS:
BAC29856.1,
AAH11457.1,
AAH19761.1,
AAH20098.1,
BAE36865.1,
BAE43184.1
Ensembl_TRS:
ENSMUST00000097473,
ENSMUST00000195015
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095081,
ENSMUSP00000142042
RefSeq:
NP_001034572.1
|
| Others |
UniRef100:
UniRef100_Q921L3,
UniRef100_Q3V4A0
UniRef90:
UniRef90_G1QE40,
UniRef90_Q921L3
UniRef50:
UniRef50_A0A0A9X7M7,
UniRef50_Q921L3
UniGene:
Mm.330045
CCDS:
CCDS15456.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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