| Type | Description |
|---|---|
| Definition | patatin-like phospholipase domain containing 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:20:00 | Genetic Ablation of Calcium-independent Phospholipase A2gamma Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice. | 31700134 |
| 2018-04-28 10:03:00 | over-expression of PNPLA8 dramatically decreases hepatic steatosis through increased autophagy in hepatocytes of high-fat diet-fed mice | 27767079 |
| 2017-07-08 12:39:00 | these results demonstrate the integrated roles of Cardiolipin and iPLA2gamma in lipid second-messenger production and mitochondrial bioenergetics during oxidative stress. | 28442572 |
| 2017-05-20 10:29:00 | Because mitochondrial membrane depolarization and calcium are known to activate iPLA2gamma, these results are consistent with salvage of myocardium after Ischemia/Reperfusion by iPLA2gamma loss of function through decreasing mPTP opening, diminishing production of proinflammatory oxidized fatty acids | 27453526 |
| 2013-08-31 10:15:00 | UCP2, functional due to fatty acids released by redox-activated mt-iPLA2gamma, suppresses mitochondrial superoxide production by its uncoupling action. | 23354121 |
| Type | IDs |
|---|---|
| Synonymous | 1200006O19Rik, AI467579, Ipla2(gamma) |
| Gene |
UniProtKB-ID:
PLPL8_MOUSE
UniprotKB:
Q8K1N1
UniParc:
UPI00000E7A75
EMBL:
AK004621,
BC019364,
AK163211,
AK168475,
BC127056,
AK145776,
AB044139
Ensembl:
ENSMUSG00000036257
KO:
mmu:67452
|
| Nucleutide sequences |
EMBL-CDS:
BAE40365.1,
BAB23417.1,
BAE26645.1,
AAH19364.1,
BAE37236.1,
AAI27057.1,
BAB97200.1
Ensembl_TRS:
ENSMUST00000043082
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043286
RefSeq:
XP_006516237.1,
NP_080440.2
|
| Others |
UniRef100:
UniRef100_Q8K1N1
UniRef90:
UniRef90_Q8K1N1
UniRef50:
UniRef50_Q9NP80
UniGene:
Mm.54126
CCDS:
CCDS36436.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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