| Type | Description |
|---|---|
| Definition | sortilin-related VPS10 domain containing receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 13:04:00 | SorCS1 and SorLA expression were markedly reduced in the frontal cerebral cortex and to a minor extent in the hippocampus, whereas SorCS3 expression was solely reduced in the frontal cerebral cortex | 31095505 |
| 2019-02-16 11:32:00 | our findings identified a novel role for VPS10P domain receptors SORCS1 and SORCS3 in hypothalamic control of metabolism through regulation of orexigenic peptide production. | 29440124 |
| 2018-01-13 14:45:00 | SorCS3 serves as a key regulator of synaptic transmission and plasticity. Results show that glutamate receptor functions are controlled by SorCS3 to secure correct functioning of excitatory synapses. The receptor plays a more central role in CA1 compared to the dentate gyrus, correlating well with the expression pattern. Reduced function of SorCS3 results in impaired synaptic mechanisms in the hippocampus. | 27935149 |
| 2015-11-07 10:38:00 | Study demonstrates that SorCS3 expression is restricted to the developing and adult nervous system | 24715575 |
| 2014-06-21 10:18:00 | Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. | 24069373 |
| Type | IDs |
|---|---|
| Synonymous | 6330404A12Rik, AW045579 |
| Gene |
UniProtKB-ID:
SORC3_MOUSE,
Q1HL22_MOUSE
UniprotKB:
Q8VI51,
Q1HL22
UniParc:
UPI000002949A
EMBL:
AK020713,
AF276314,
DQ479928
Ensembl:
ENSMUSG00000063434
KO:
mmu:66673
|
| Nucleutide sequences |
EMBL-CDS:
AAL36983.1,
ABF48507.1
Ensembl_TRS:
ENSMUST00000078880
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077919
RefSeq:
NP_079972.1
|
| Others |
UniRef100:
UniRef100_Q8VI51
UniRef90:
UniRef90_Q8VI51
UniRef50:
UniRef50_Q8WY21-4
UniGene:
Mm.70980
CCDS:
CCDS38020.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员