| Type | Description |
|---|---|
| Definition | sterol O-acyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:33:00 | SOAT1 promotes mevalonate pathway dependency in pancreatic cancer. | 32633781 |
| 2021-02-27 13:54:00 | A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression. | 32646003 |
| 2020-10-24 14:05:00 | Association Between LOX-1, LAL, and ACAT1 Gene and Carotid Plaque in a Northern Chinese Population. | 32101051 |
| 2020-07-18 12:05:00 | cryo-electron microscopy structure of human ACAT1(SOAT1) as a dimer of dimers; structural and biochemical characterization helps to rationalize the preference of ACAT1 for unsaturated acyl chains, and provides insight into the catalytic mechanism of enzymes within the MBOAT family | 32433614 |
| 2020-07-11 11:53:00 | cryo-electron microscopy structure of human ACAT1 (SOAT1) in complex with nevanimibe, an inhibitor that is in clinical trials for the treatment of congenital adrenal hyperplasia | 32433613 |
| Type | IDs |
|---|---|
| Synonymous | ACACT, ACAT, ACAT-1, ACAT1, SOAT, STAT |
| Gene |
UniProtKB-ID:
SOAT1_HUMAN
UniprotKB:
P35610
UniParc:
UPI00001408E7,
UPI0000E1EE62,
UPI0000071233
EMBL:
L21934,
AK300551,
AK290659,
AL512326,
BC028940,
AL451075,
CH471067
Ensembl:
ENSG00000057252
KO:
hsa:6646
|
| Nucleutide sequences |
EMBL-CDS:
EAW91043.1,
BAF83348.1,
AAC37532.2,
EAW91044.1,
BAG62257.1,
AAH28940.1
Ensembl_TRS:
ENST00000540564,
ENST00000539888,
ENST00000367619
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000441356,
ENSP00000445315,
ENSP00000356591
RefSeq:
NP_003092.4,
NP_001239440.1,
XP_011508213.1,
XP_011508214.1,
NP_001239441.1
|
| Others |
UniRef100:
UniRef100_P35610
UniRef90:
UniRef90_P35610
UniRef50:
UniRef50_P35610
UniGene:
Hs.445588
CCDS:
CCDS1330.1,
CCDS58048.1,
CCDS58047.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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