| Type | Description |
|---|---|
| Definition | ER membrane protein complex subunit 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 11:26:00 | Adenovirus-mediated ectopic overexpression of EMC6 (Ad5-EMC6) decreases the activity of ERK1/2, down-regulates the levels of BCL-2 and increases the ratio of BAX/BCL-2. Ad5-EMC6 mediates anti-tumor activity through the mitochondrial apoptosis pathway. Ad5-EMC6 enhances the sensitivity of gastric cancer cells to the etoposide. | 30982575 |
| Type | IDs |
|---|---|
| Synonymous | 0610009E20Rik, 0610025L18Rik, Tmem93 |
| Gene |
UniProtKB-ID:
EMC6_MOUSE
UniprotKB:
Q9CQW0
UniParc:
UPI00000212D2
EMBL:
AK003198,
BC022104,
AK004149,
AK012769,
AK002385,
AL670399
Ensembl:
ENSMUSG00000047260
KO:
mmu:66048
|
| Nucleutide sequences |
EMBL-CDS:
BAB28457.1,
BAB22636.1,
BAB22059.1,
AAH22104.1,
BAB23194.1
Ensembl_TRS:
ENSMUST00000054952,
ENSMUST00000108480
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104120,
ENSMUSP00000060892
RefSeq:
NP_079594.1,
NP_001161942.1
|
| Others |
UniRef100:
UniRef100_Q9BV81
UniRef90:
UniRef90_Q9BV81
UniRef50:
UniRef50_Q9BV81
UniGene:
Mm.73608
CCDS:
CCDS24999.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30982575 |
Biochem. Biophys. Res. Commun. Riyong Li , Xiaokun Wang , Xuan Zhang , Jiahong Yu , Jinqiu Feng , Ping Lv , Yaxin Lou , Yingyu Chen |
2019-06-04 | - |
| 30550785 |
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Cell Hyeonwoo Kim , Christiane D Wrann , Mark Jedrychowski , Sara Vidoni , Yukiko Kitase , Kenichi Nagano , Chenhe Zhou , Joshua Chou , Virginia-Jeni A Parkman , Scott J Novick , Timothy S Strutzenberg , Bruce D Pascal , Phuong T Le , Daniel J Brooks , Alexander M Roche , Kaitlyn K Gerber , Laura Mattheis , Wenjing Chen , Hua Tu , Mary L Bouxsein , Patrick R Griffin , Roland Baron , Clifford J Rosen , Lynda F Bonewald , Bruce M Spiegelman |
2018-12-13 | - |
| 26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
| 25737280 |
Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes Dev. Jernej Murn , Kathi Zarnack , Yawei J Yang , Omer Durak , Elisabeth A Murphy , Sihem Cheloufi , Dilenny M Gonzalez , Marianna Teplova , Tomaž Curk , Johannes Zuber , Dinshaw J Patel , Jernej Ule , Nicholas M Luscombe , Li-Huei Tsai , Christopher A Walsh , Yang Shi |
2015-03-01 |
Sf3b3,
Pls3,
Xpo1,
Slc38a1,
Rrn3,
Hat1,
Ogt,
Foxp1,
Atp6v1h,
Pnrc1,
Ppp1r15b,
Pkn2,
Rap1a,
Acat1,
Cse1l,
Abcb7,
Actb,
Prdx3,
Ap1g1,
Arf1,
Arf4,
Arf5,
Arhgap5,
Atp2a2,
Atp5a1,
Atpif1,
Phb2,
Birc6,
Calm1,
Calm2,
Calm3,
Ctnna1,
Ctnnb1,
Cbx3,
Cbx5,
Cct4,
Cct5,
Cct8,
Cdc42,
Copa,
Cox5a,
Cox7a2,
Dpysl2,
Csnk2b,
Ctsb,
Dhx15,
Ddx5,
Dync1h1,
Dst,
Mapre1,
Eef1a1,
Eef2,
Eif3a,
Eif4a1,
Eif4a2,
Eif4g2,
Gdi1,
Gdi2,
Gfpt1,
Ggps1,
Gls,
Glud1,
Rack1,
Pdia3,
H3f3b,
Hdac2,
Hint1,
Hmgcr,
Hn1,
Hnrnpab,
Hnrnpl,
Hspd1,
Hsp90ab1,
Hsp90aa1,
Hspa4,
Hspa9,
Hspe1,
Id3,
Kpnb1,
Eif3e,
Itgb1,
Itm2b,
Kpna4,
Kpna6,
Kras,
Ldha,
Nup155,
Matr3,
Mcl1,
Msh6,
Laptm4a,
Nap1l4,
Ncl,
Nfib,
Ogdh,
Pdcd4,
Slc25a3,
Plaa,
Ppp1cb
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 17015433 |
Genes Dev. Alexei V Evsikov , Joel H Graber , J Michael Brockman , Ales Hampl , Andrea E Holbrook , Priyam Singh , John J Eppig , Davor Solter , Barbara B Knowles |
2006-10-01 |
Oog3,
Gm10637,
Cphx2,
Gm10436,
Gm15501,
Gm3139,
Gm3143,
Gm3259,
Gm3286,
Gm4566,
Gm14635,
Gm11238,
Gm12130,
Gm38425,
Oas1d,
Nfxl1,
A730082K24Rik,
Mtus1,
Dcun1d2,
Lrrc49,
Ndufb11,
Golm1,
Chmp7,
Cmc4,
AU021063,
Cops8,
Rnf20,
2610305D13Rik,
Serpinc1,
Bmp15,
Birc6,
Aspm,
Cnih1,
Daxx,
Ebp,
Mark2,
Epc1,
Fgfr2,
Fkbp2,
Fkbp8,
Gart,
Gclm,
Gpr19,
Trip12,
Hnrnpc,
Eif2ak1,
Ica1,
Itpr1,
Lama5,
Lamc2,
Glcci1,
Mfap2,
Mtf1,
Mthfd2,
Usp34,
Myo5b,
Nf2,
Nfyc,
Nudc,
Odf2,
Omt2a,
Slc25a15,
Igbp1,
Per3,
Pex7,
Abcb1b,
Plaa,
Plat,
Ppp5c,
Proc,
Ptprr,
Oog1,
Gm13103,
Klf11,
Rdx,
Rnaseh1,
Trim30a,
Siah1b,
Bptf,
Spin1,
Esrp1,
Aurkc,
Fanci,
Surf4,
Suv39h1,
Pdlim2,
Tcl1,
Tdrd5,
Mcu,
Os9,
Clint1,
Heatr6,
Gm11545,
Tex264,
Cirh1a,
Eif4e1b,
Top1,
Ttk,
Ubc
|
| 16141072 |
The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C Schönbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) |
2005-09-02 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员