| Type | Description |
|---|---|
| Definition | ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
| Date | Results | Publications |
|---|---|---|
| 2012-04-21 10:38:00 | ADAMTS4 mRNA increased at 3 h after myocardial infarction, peaked at 6 h, then decreased rapidly; protein levels of ADAMTS4 were significantly increased at 6 h, 12 h, 24 h and 3 d after MI. | 21257285 |
| 2011-04-09 10:20:00 | Inhibition of aggrecanase-1 decreases aggrecan degradation in cultured rat chondrocytes. | 19778785 |
| 2011-01-08 10:53:00 | Together these data demonstrate that inhibition of endogenous aggrecanases facilitates chondrocyte differentiation and chondrocyte-engineered cartilage formation in vitro. | 20632367 |
| 2010-01-21 00:00:00 | This study suggests that dental pulp cells, odontoblasts, cementoblasts, cementocytes, periodontal ligament cells, osteoblasts and osteocytes may be involved in both production and degradation of versican with secreting ADAMTS1, ADAMTS4 and ADAMTS5. | 16200461 |
| 2010-01-21 00:00:00 | ADAMTS-5 mainly contributed to ECM metabolism in growth plate and condylar cartilage during growth. ADAMTS-1 and ADAMTS-4 may be involved in ECM turn over in articular cartilage. | 16583222 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
ATS4_RAT
UniprotKB:
Q9ESP7
UniParc:
UPI0000126628
EMBL:
AB042272,
AB042273,
AB042271
KO:
rno:66015
|
| Nucleutide sequences |
EMBL-CDS:
BAB16475.1,
BAB16474.1,
BAB16473.1
|
| Protein sequencees |
RefSeq:
NP_076449.1
|
| Others |
UniRef100:
UniRef100_Q9ESP7
UniRef90:
UniRef90_Q9ESP7
UniRef50:
UniRef50_Q9ESP7
UniGene:
Rn.64490
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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