| Type | Description |
|---|---|
| Definition | bone morphogenetic protein 8b |
| Date | Results | Publications |
|---|---|---|
| 2021-01-04 09:20:00 | BMP8B is upregulated in human NASH in hepatocytes and HSC. The absence of BMP8B prevents HSC activation, reduces inflammation and affects the wound-healing responses, thereby limiting NASH progression. | 32694734 |
| 2021-01-02 12:52:00 | Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis. | 32694734 |
| 2020-01-04 11:27:00 | The data indicate that BMP8B enhances different pathophysiological steps of non-alcoholic fatty liver disease (NAFLD) progression and suggest BMP8B as a promising prognostic marker and therapeutic target for NAFLD and, potentially, also for other chronic liver diseases. | 31096638 |
| 2017-11-04 12:00:00 | Acetylated H3K9 and H4K16 levels at BMP8B were increased in gastric cancer (GC) compared to nontumors (P < 0.05). However, reduced levels of acetylated H3K9 and H4K16 were associated with poorly differentiated GC (P < 0.05). | 27748538 |
| 2015-10-31 10:23:00 | Study found that BMP8B was downregulated in pancreatic cancer tissues and BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer. | 25176058 |
| Type | IDs |
|---|---|
| Synonymous | BMP8, OP2 |
| Gene |
UniProtKB-ID:
BMP8B_HUMAN
UniprotKB:
P34820
UniParc:
UPI00015E0B9B,
UPI000013C9D9
EMBL:
AY303955,
BC108678,
AL033527,
M97016,
AL049824
Ensembl:
ENSG00000116985
KO:
hsa:656
|
| Nucleutide sequences |
EMBL-CDS:
AAI08679.1,
AAP74560.1,
AAB01360.1
Ensembl_TRS:
ENST00000372827
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000361915
RefSeq:
XP_011540327.1,
XP_011540324.1,
XP_024305067.1,
XP_016857645.1,
XP_011540326.2,
NP_001711.2,
XP_016857644.1,
XP_005271206.1
|
| Others |
UniRef100:
UniRef100_P34820
UniRef90:
UniRef90_Q7Z5Y6
UniRef50:
UniRef50_Q7Z5Y6
UniGene:
Hs.734367
CCDS:
CCDS444.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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