| Type | Description |
|---|---|
| Definition | protein kinase AMP-activated catalytic subunit alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:49:00 | Melatonin improves mitochondrial biogenesis through the AMPK/PGC1alpha pathway to attenuate ischemia/reperfusion-induced myocardial damage. | 32305957 |
| 2020-06-20 12:42:00 | CAMKII plays a key role in mediating caloric restriction-induced AMPK activation through increased production of hydrogen peroxide. | 31100477 |
| 2020-02-29 11:32:00 | Both metformin and exenatide can improve the reproductive and endocrine functions of rats with polycystic ovary syndrome (PCOS) via the AMPKalpha-SIRT1 pathway, which may be the molecular mechanism for insulin resistance in PCOS and could possibly serve as a therapeutic target. | 31526389 |
| 2020-01-25 14:03:00 | Overexpression of the miR-26a or si-PFKFB3 provides an elevation in cell proliferation. Our study suggests that the miR-26a RNA alleviates lower extremity IRI-induced VEC injury in rats through the activation of the AMPK(AMPK alpha1) pathway by inhibiting PFKFB3. | 30132885 |
| 2019-07-27 12:07:00 | CHLZT and AICAR increased the levels of p-AMPKalpha and PPARgamma in the NAFLD liver tissues and HepG2 cells, but decreased the levels of ACC-a, p-ACC-a, SREBP-2, and 3-hydroxyl-3-methylglutaryl-coenzyme A reductase (HMGR). | 30291215 |
| Type | IDs |
|---|---|
| Synonymous | AMPKalpha1 |
| Gene |
UniProtKB-ID:
AAPK1_RAT
UniprotKB:
P54645
UniParc:
UPI0001AE4F47
EMBL:
CH474048,
U40819
Ensembl:
ENSRNOG00000012799
KO:
rno:65248
|
| Nucleutide sequences |
EMBL-CDS:
AAC52355.1
Ensembl_TRS:
ENSRNOT00000017626
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000017626
RefSeq:
NP_062015.2
|
| Others |
UniRef100:
UniRef100_P54645
UniRef90:
UniRef90_Q5EG47
UniRef50:
UniRef50_Q13131
UniGene:
Rn.87789
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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