| Type | Description |
|---|---|
| Definition | porcupine O-acyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:28:00 | Porcupine Inhibitor LGK974 Downregulates the Wnt Signaling Pathway and Inhibits Clear Cell Renal Cell Carcinoma. | 32104684 |
| 2020-02-29 11:34:00 | findings demonstrate that dual PORCN and PI3K/mTOR inhibition is a potential strategy for treating Wnt-driven pancreatic cancers | 31391551 |
| 2019-12-21 11:44:00 | Targeting Porcupine or the CBP/beta-catenin interaction seems to be an effective strategy for the inhibition of canonical Wnt signaling in head and neck carcinoma cells. | 31089983 |
| 2019-04-13 10:09:00 | Together, these results provide discrete, high-resolution biochemical insights into the mechanism of PORCN-mediated Wnt acylation and pave the way for further detailed biochemical and structural studies. | 30420431 |
| 2018-04-21 11:57:00 | Case Report: mosaicism for PORCN mutations in focal dermal hypoplasia (Goltz Syndrome). | 28293688 |
| Type | IDs |
|---|---|
| Synonymous | DHOF, FODH, MG61, PORC, PPN |
| Gene |
UniProtKB-ID:
PORCN_HUMAN
UniprotKB:
Q9H237
UniParc:
UPI0000071358,
UPI000013C75C,
UPI000014187F,
UPI000034ECE4,
UPI0000141875
EMBL:
CH471224,
L08239,
AF317058,
AF317061,
AK316378,
BC019080,
AF317060,
AK314745,
AF317059,
AF196972
Ensembl:
ENSG00000102312
KO:
hsa:64840
|
| Nucleutide sequences |
EMBL-CDS:
AAA74510.1,
AAH19080.1,
BAH14749.1,
EAW50780.1,
AAG39630.1,
AAG39631.1,
AAG39628.1,
BAG37285.1,
AAG39629.1
Ensembl_TRS:
ENST00000359882,
ENST00000361988,
ENST00000355961,
ENST00000367574,
ENST00000537758,
ENST00000326194
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354978,
ENSP00000322304,
ENSP00000348233,
ENSP00000446401,
ENSP00000352946,
ENSP00000356546
RefSeq:
XP_024308193.1,
NP_073736.2,
NP_001269096.1,
NP_982300.1,
NP_982301.1,
NP_982299.1
|
| Others |
UniRef100:
UniRef100_Q9H237
UniRef90:
UniRef90_Q9H237
UniRef50:
UniRef50_Q9JJJ7
UniGene:
Hs.386453
CCDS:
CCDS14297.1,
CCDS14299.1,
CCDS14298.1,
CCDS14296.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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