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64768 IPPK

64768

IPPK

inositol-pentakisphosphate 2-kinase

protein-coding

Homo sapiens

基因描述

Type Description
Definition inositol-pentakisphosphate 2-kinase

研究结论

Date Results Publications
2019-09-21 10:13:00 Higher urine IPP2K/Cr is associated with less severe kidney lesions at baseline and with preservation of kidney structure over 5 yr in individuals with type 1 diabetes and no clinical evidence of DKD at baseline. 30132343
2018-08-04 10:43:00 These results imply that DBP5, GLE1 and IP6 have a conserved and individual function in the cytoplasmic mRNA expression. Variations in phenotype are due to the difference in each function of DBP5, GLE1 and IPPK in intracellular mRNA metabolism. 29746542
2016-09-03 12:09:00 IP6 synthase, Ins(1,3,4,5,6)P5 2-kinase (IPPK/IP5K) binds to cullins. Depleting IP5K increases the percentage of neddylated, active Cul1 and Cul4A, and decreases levels of the Cul1/4A substrates p27 and p21. 26976604
2014-02-22 12:13:00 IPK1 substrate selection is linked to the ability of each potential substrate to stabilize IPK1. 24165122
2010-01-21 00:00:00 identified a genomic DNA sequence on chromosome 9 that encodes inositol 1,3,4,5,6-pentakisphosphate 2-kinase; characterization of the enzyme 12084730

名称对应

Type IDs
Synonymous C9orf12, INSP5K2, IP5K, IPK1, bA476B13.1
Gene
UniProtKB-ID: IPPK_HUMAN
UniprotKB: Q9H8X2
UniParc: UPI000006EBCA
EMBL: AL157827, AK024267, AF351202, BC026154, AK023225, AL137074, AF520811
Ensembl: ENSG00000127080
KO: hsa:64768
Nucleutide sequences
EMBL-CDS: BAB14866.1, AAM75353.1, AAH26154.1, BAB14476.1, AAK69692.1
Ensembl_TRS: ENST00000287996
Protein sequencees
Ensembl_PRO: ENSP00000287996
RefSeq: NP_073592.1, XP_016870530.1
Others
UniRef100: UniRef100_Q9H8X2
UniRef90: UniRef90_Q9H8X2
UniRef50: UniRef50_Q9H8X2
UniGene: Hs.459896, Hs.713775
CCDS: CCDS6699.1

全选

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