Type | Description |
---|---|
Definition | amyloid beta precursor like protein 2 |
Date | Results | Publications |
---|---|---|
2018-02-24 11:08:00 | alanine in APP- intracellular domain(ICD) and the proline in APLP2-ICD lie directly behind a conserved caspase cleavage site | 26921470 |
2016-12-31 11:46:00 | This study demonstrated that the downregulation of amyloid beta precursor in Rat Medial Temporal Lobe Cortex Following Transient Global Brain ischemia. | 26890784 |
2012-07-14 10:33:00 | Findings demonstrate that both acute and chronic Immobilization Stress lead to gene transcriptional changes of beta-actin, APP and MAPK-1. These changes may lead to cognitive deterioration, and the development of Alzheimer disease. | 22724288 |
2010-01-21 00:00:00 | The expression of APLP2 is up-regulated in the striatum following dopaminergic denervation | 12372026 |
2010-01-21 00:00:00 | The APLP2 gene has both a GAGA sequence and a CAGA box immediately upstream of a position corresponding to the APP gene CAGA box. | 15208260 |
Type | IDs |
---|---|
Synonymous | APLP-2, Apph, WALPLP2 |
Gene | |
Nucleutide sequences | |
Protein sequencees |
RefSeq:
NP_037038.1,
NP_071965.1
|
Others |
UniGene:
Rn.1423,
Rn.129285
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
26921470 |
Neurobiol. Dis. Emilie Trillaud-Doppia , Nicolas Paradis-Isler , Jannic Boehm |
2016-07-01 | - |
26890784 |
J. Alzheimers Dis. Ryszard Pluta , Janusz Kocki , Marzena UÅamek-KozioÅ , Alicja Petniak , Paulina Gil-Kulik , SÅawomir Januszewski , Jacek Bogucki , MirosÅaw JabÅoÅski , Judyta Brzozowska , Wanda Furmaga-JabÅoÅska , Anna Bogucka-Kocka , StanisÅaw J Czuczwar |
2016-02-17 | - |
25683482 |
J. Neurochem. Sarah L Cousins , Wei Dai , F Anne Stephenson |
2015-06-01 |
APLP1,
APLP2
|
22724288 |
[Acute and chronic stress induced changes in gene transcriptions related to Alzheimer's disease]. Ideggyogy Sz Petra Sántha , Magdolna Pákáski , Orsike Fazekas , Szabina Szucs , Eszter Klára Fodor , János Kálmán , Sára Kálmán , Gyula Szabó , Zoltán Janka , János Kálmán |
2012-05-30 |
Mapk1,
Aplp2,
Actb
|
19946888 |
Defining the membrane proteome of NK cells. J Mass Spectrom Dhimankrishna Ghosh , Dustin Lippert , Oleg Krokhin , John P Cortens , John A Wilkins |
2010-01-01 |
MED6,
PDCD6IP,
MED16,
PIGK,
DNAJB6,
FARSB,
DNM1L,
ABCF2,
HUWE1,
ARPC3,
ACTR3,
ACTR2,
RAD50,
PREB,
ACTR1B,
LRPPRC,
TRAP1,
BCAP31,
PLXNC1,
LPCAT3,
TNK2,
PSME3,
MPHOSPH9,
FLOT1,
DDX39A,
AK6,
ADAM10,
PLIN3,
CALCOCO2,
CDK9,
ABCC4,
ZMPSTE24,
AKAP8,
BET1,
MARCH6,
KATNB1,
ADAR,
EMC8,
BTN3A3,
ATP8A1,
NDC80,
CDIPT,
PGRMC2,
TUBGCP3,
ECI2,
COG5,
SLC25A17,
LRRC41,
SYNCRIP,
MYBBP1A,
DDX17,
CHERP,
HYOU1,
IPO7,
NOP56,
ARL6IP5,
HTATIP2,
AGPAT1,
ARFGEF2,
RABAC1,
SLU7,
PRPF8,
PAICS,
CENPE,
PMVK,
KHDRBS1,
CELF1,
GNA13,
CFL1,
MGEA5,
YME1L1,
STAG2,
CTSC,
GIPC1,
HBS1L,
TUBGCP2,
PGRMC1,
MAN1A2,
PNPLA6,
MAGED2,
ADCY3,
EHD1,
TOMM34,
ERP29,
YWHAQ,
ASCC3,
GCN1,
IMMT,
ILVBL,
SLC27A4,
SLC27A3,
KIF2C,
GLIPR1,
CPSF6,
DDX52,
WWP2,
CNTRL,
CHD4,
KRR1
|
19199708 |
J. Proteome Res. Mireya Gonzalez-Begne , Bingwen Lu , Xuemei Han , Fred K Hagen , Arthur R Hand , James E Melvin , John R Yates |
2009-03-01 |
GNPDA1,
PDCD6IP,
ACTR2,
ADGRG2,
ATP6AP2,
AKR1A1,
ST3GAL6,
CAP1,
VAT1,
HYOU1,
PRDX4,
OLFM4,
CFL1,
CTSC,
MAN1A2,
EHD1,
YWHAQ,
PRSS23,
SLC6A14,
PARK7,
CHST14,
MGAT4A,
TWF2,
C1QTNF3,
SLC26A9,
FAM129A,
CLU,
CLTC,
HIST4H4,
ZG16B,
CNP,
HIST2H3C,
TPRG1L,
COL6A1,
COL6A2,
COPA,
TMPRSS11B,
CPD,
S100A16,
BPIFA2,
A2ML1,
CST3,
CST4,
CST5,
CSTB,
BROX,
CTNNB1,
CTNND1,
PROM2,
CTSB,
PPM1L,
CD55,
DAG1,
GBP6,
AEBP1,
DDX3X,
DEFA1,
DMBT1,
DYNC1H1,
DPP4,
DSC2,
DSG2,
DSP,
TOR1A,
ECM1,
EEF1A1,
EEF2,
KRT78,
ANO6,
ENO1,
ESD,
EVPL,
EXT2,
ALDH1A1,
FAT2,
SLC37A2,
GPC4,
ALDOA,
ERP44,
GANAB,
PLCB1,
FOLR1,
CES3,
PLD3,
FUT2,
FUT3,
FUT6,
FUT8,
NPNT,
PRDX5,
GAPDH,
PHGDH,
B3GAT3,
B4GALT1,
VPS4A,
TOR1B,
GLRX,
AMY1A,
GMDS
|
17920016 |
Neuron Qiang Liu , Celina V Zerbinatti , Juan Zhang , Hyang-Sook Hoe , Baiping Wang , Sarah L Cole , Joachim Herz , Louis Muglia , Guojun Bu |
2007-10-04 | - |
17556541 |
Proc. Natl. Acad. Sci. U.S.A. Yun-wu Zhang , Ruishan Wang , Qiang Liu , Han Zhang , Francesca-Fang Liao , Huaxi Xu |
2007-06-19 |
Aplp2,
App,
Psen1,
Psen2
|
16193067 |
Homo- and heterodimerization of APP family members promotes intercellular adhesion. EMBO J. Peter Soba , Simone Eggert , Katja Wagner , Hanswalter Zentgraf , Katjuscha Siehl , Sylvia Kreger , Alexander Löwer , Andreas Langer , Gunter Merdes , Renato Paro , Colin L Masters , Ulrike Müller , Stefan Kins , Konrad Beyreuther |
2005-10-19 |
Aplp1,
Aplp2,
App,
APLP1,
APLP2,
APP
|
15689559 |
J. Neurosci. Pei Wang , Guang Yang , Dennis R Mosier , Paul Chang , Tahire Zaidi , Yan-Dao Gong , Nan-Ming Zhao , Bertha Dominguez , Kuo-Fen Lee , Wen-Biao Gan , Hui Zheng |
2005-02-02 | - |
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