| Type | Description |
|---|---|
| Definition | glutaredoxin |
| Date | Results | Publications |
|---|---|---|
| 2010-08-02 12:19:00 | Grx1 decreases by ~40% in 2-yr-old Fischer 344 rat hearts vs 6-mo-old controls. Grx1 knockdown in H9c2 cardiomyocytes increases apoptosis, & decreases NFkappaB transcription,& production of Bcl-2 & Bcl-xL. | 19938943 |
| 2010-05-31 11:43:00 | study reports Cys23 of thioltransferase is an essential residue for catalytic activity & the other Cys26 is also important but Cys79 & Cys83 were not essential; for protection of cells from oxidative stress active thioltransferase is essential | 20175144 |
| 2010-01-21 00:00:00 | NADPH/glutaredoxin/thioredoxin redox regulation mediates a novel signaling pathway of nutrient-induced insulin secretion. | 15983215 |
| 2010-01-21 00:00:00 | role of Grx in the maintenance of functional oocytes and in luteal cells surviving the regression process | 15956334 |
| 2010-01-21 00:00:00 | NO increased the S-glutathiolation of SERCA, and adenoviral overexpression of glutaredoxin-1 prevented both the HNO-stimulated oxidative modification of SERCA and its activation. | 19265039 |
| Type | IDs |
|---|---|
| Synonymous | Glrx1, Grx |
| Gene |
UniProtKB-ID:
GLRX1_RAT
UniprotKB:
Q9ESH6
UniParc:
UPI000016799C
EMBL:
AF319950,
AF167981,
BC061555
Ensembl:
ENSRNOG00000012183
KO:
rno:64045
|
| Nucleutide sequences |
EMBL-CDS:
AAK07419.1,
AAH61555.1,
AAF89637.3
Ensembl_TRS:
ENSRNOT00000016372
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016372
RefSeq:
NP_071614.1
|
| Others |
UniRef100:
UniRef100_Q9ESH6
UniRef90:
UniRef90_Q9ESH6
UniRef50:
UniRef50_Q9ESH6
UniGene:
Rn.1484
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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