| Type | Description |
|---|---|
| Definition | beta-carotene oxygenase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:12:00 | beta-Carotene Oxygenase 1 Activity Modulates Circulating Cholesterol Concentrations in Mice and Humans. | 32433733 |
| 2019-07-06 13:03:00 | provided novel experimental evidence that BCO1 and BCO2 could play a significant role in maintaining normal hepatic lipid and cholesterol homeostasis, potentially through the regulation of the FXR/miR-34a/SIRT1 pathway | 30006135 |
| 2017-07-01 12:04:00 | This is the first demonstration that Bco1 disruption lowers murine circulating testosterone levels and thereby reduces prostatic androgen receptor signaling and prostatic cellular proliferation, further supporting the role of this protein in processes more diverse than carotenoid cleavage. | 27629887 |
| 2015-06-27 10:23:00 | tissue- and sex-specific effects of beta-carotene 15,15' oxygenase (BCO1) on retinoid and lipid metabolism | 25602705 |
| 2015-01-24 11:01:00 | BCO1 modulates heart metabolism and function, possibly by altering levels of cofactors required for the actions of nuclear hormone receptors | 25260612 |
| Type | IDs |
|---|---|
| Synonymous | Bcdo, Bcdo1, Bcmo1, CMO1, Cmoi, beta-CD, betaCMOOX |
| Gene |
UniProtKB-ID:
BCDO1_MOUSE,
E9Q321_MOUSE,
Q05AC0_MOUSE
UniprotKB:
Q9JJS6,
E9Q321,
Q05AC0
UniParc:
UPI0001AE826C,
UPI00000238D1
EMBL:
AF271298,
BC125328,
AY114295,
AY114300,
AF294899,
AY114297,
AY114302,
AJ278064,
AY114298,
AK054171,
AY114301,
BC125330,
AC108436,
AY114299,
AC121116,
AY114296,
AY114294
Ensembl:
ENSMUSG00000031845
KO:
mmu:63857
|
| Nucleutide sequences |
EMBL-CDS:
AAM76677.1,
AAG15381.1,
BAC35679.1,
AAG33982.1,
CAB92531.2,
AAI25329.1,
AAI25331.1
Ensembl_TRS:
ENSMUST00000034308,
ENSMUST00000167370,
ENSMUST00000176860
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034308,
ENSMUSP00000132042,
ENSMUSP00000134815
RefSeq:
NP_067461.2,
NP_001156500.1,
XP_011246783.1
|
| Others |
UniRef100:
UniRef100_E9Q321,
UniRef100_Q9JJS6
UniRef90:
UniRef90_E9Q321,
UniRef90_Q9JJS6
UniRef50:
UniRef50_Q9HAY6
UniGene:
Mm.174133
CCDS:
CCDS22697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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