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63834 Capn10

63834

Capn10

calpain 10

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition calpain 10

研究结论

Date Results Publications
2012-08-18 10:43:00 diabetes-induced renal mitochondrial dysfunction and renal injury may directly result from the loss of renal calpain 10 22568896
2010-01-21 00:00:00 These results provide evidence that several previously postulated splice variants of calpain 10 are localized to the mitochondria in kidneys of rabbits, rats, and mice. 18054326
2010-01-21 00:00:00 "Calpain 10 (CAPN10) is reported linked with type 2 diabetes in certain human populations..." "Levels of mRNA for type 2 diabetes-related genes such as ...CPN10 were quantified in WBC...in OLETF rats... known to initiate type 2 diabetes at 18 weeks..." 14646187
2010-01-21 00:00:00 Data show that calpain 10 is a mitochondrially targeted and is a mediator of mitochondrial dysfunction through the cleavage of Complex I subunits and activation of the mitochondrial permeability transition. 16790502
2010-01-21 00:00:00 195 gly-ser SNP might be associated with susceptibility to type 2 diabetes mellitus 14658759

名称对应

Type IDs
Gene
UniProtKB-ID: CAN10_RAT, Q5U345_RAT
UniprotKB: Q9ES66, Q5U345
UniParc: UPI000045605C, UPI0000126EA5
EMBL: AF227909, BC085725
KO: rno:63834
Nucleutide sequences
EMBL-CDS: AAG09736.3, AAH85725.1
Protein sequencees
RefSeq: NP_113861.1
Others
UniRef100: UniRef100_Q5U345, UniRef100_Q9ES66
UniRef90: UniRef90_Q9ES66, UniRef90_Q5U345
UniRef50: UniRef50_Q9ES66, UniRef50_A0A0Q3MAX7
UniGene: Rn.176334

全选

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