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6223 RPS19

6223

RPS19

ribosomal protein S19

protein-coding

Homo sapiens

基因描述

Type Description
Definition ribosomal protein S19

研究结论

Date Results Publications
2019-08-17 10:23:00 Similar to the MIF-knockout mice, treatment with RPS19, but not the mutant RPS19, suppressed cisplatin-induced acute kidney injury (AKI). Mechanistically, we found that both genetic knockout and pharmacological inhibition of MIF protected against AKI by inactivating the CD74-nuclear factor kappaB (NF-kappaB) signaling. 30077612
2019-08-03 11:14:00 Patients with RPS19 mutations had the fewest number of defects, while patients with RPL5 had the greatest number of birth defects. This is the first study to show differences between Diamond-Blackfan anemia (DBA) genetic groups with regards to treatment. 29044489
2018-08-18 11:07:00 Whole exome sequencing in the differential diagnosis of Diamond-Blackfan anemia: Clinical and molecular study of three patients with novel RPL5 and mosaic RPS19 mutations 28376382
2018-04-21 12:02:00 Study shows that the depletion of RPS19 causes a reduction of 47S rRNA synthesis in a number of cell lines of different origins. 27734913
2017-10-21 12:34:00 The results show that RPS19, RPS21 or RPS24 are upregulated in malignant tissue and may serve as putative biomarkers for prostate cancer. 29016636

名称对应

Type IDs
Synonymous DBA, DBA1, S19, eS19
Gene
UniProtKB-ID: RS19_HUMAN, B0ZBD0_HUMAN
UniprotKB: P39019, B0ZBD0
UniParc: UPI0000161C03
EMBL: EU326300, BC018616, BC000023, AF092906, M81757, AF092907, BC007615, AB007155, AK311786, CH471126
Ensembl: ENSG00000105372
KO: hsa:6223
Nucleutide sequences
EMBL-CDS: AAH07615.1, AAH18616.1, BAA28593.1, AAH00023.1, AAD13668.1, AAA89070.1, EAW57072.1, EAW57071.1, ACA05898.1, BAG34729.1, EAW57073.1
Gene_ORFName: hCG_1995572
Ensembl_TRS: ENST00000600467, ENST00000593863, ENST00000598742
Protein sequencees
Ensembl_PRO: ENSP00000470972, ENSP00000469228, ENSP00000470004
RefSeq: NP_001308414.1, NP_001308412.1, NP_001013.1, NP_001308413.1, XP_016882602.1
Others
UniRef100: UniRef100_P39019
UniRef90: UniRef90_P39019
UniRef50: UniRef50_P39019
UniGene: Hs.438429
CCDS: CCDS12588.1

全选

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