| Type | Description |
|---|---|
| Definition | BCR activator of RhoGEF and GTPase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:12:00 | Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells. | 32203161 |
| 2020-09-12 15:57:00 | Novel mutations in the kinase domain of BCR-ABL gene causing imatinib resistance in chronic myeloid leukemia patients. | 30787317 |
| 2020-08-15 19:05:00 | Preclinical development of a novel BCR-ABL T315I inhibitor against chronic myeloid leukemia. | 31837444 |
| 2020-07-04 10:08:00 | Study reports principal transcript variants of BCR/ABL fusion gene in Iraqi chronic myeloid leukemia patients; interrelation between these variants and their association with different aspects of the disease such as age, sex, hemoglobin, white blood cell count, and platelet count. | 31206255 |
| 2020-06-27 10:54:00 | The presence of e13a2 and e14a2 BCR/ABL1 transcripts in the peripheral blood of healthy individuals and relatives of the chronic myeloid leukemia patients. | 31882420 |
| Type | IDs |
|---|---|
| Synonymous | ALL, BCR1, CML, D22S11, D22S662, PHL |
| Gene |
UniProtKB-ID:
BCR_HUMAN
UniprotKB:
P11274
UniParc:
UPI000016A088,
UPI00001AEE0D
EMBL:
M64437,
X02596,
Y00661,
X52829,
M15025,
U07000,
AB209991,
X52828,
X14676
Ensembl:
ENSG00000186716
KO:
hsa:613
|
| Nucleutide sequences |
EMBL-CDS:
CAA68676.1,
BAE06073.1,
CAA26441.1,
AAB60388.1,
CAA37011.1,
CAA32806.1,
AAA35594.1,
CAA37010.1
Ensembl_TRS:
ENST00000305877,
ENST00000359540
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000352535,
ENSP00000303507
RefSeq:
NP_004318.3,
NP_067585.2
|
| Others |
UniRef100:
UniRef100_P11274
UniRef90:
UniRef90_P11274
UniRef50:
UniRef50_P11274
UniGene:
Hs.517461,
Hs.715409
CCDS:
CCDS13806.1,
CCDS13807.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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