| Type | Description |
|---|---|
| Definition | calcium/calmodulin-dependent protein kinase kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-11-12 11:24:00 | Site-directed mutagenesis analysis revealed that Leu(358) in CaMKKbeta/Ile(322) in CaMKKalpha confer, at least in part, a distinct recognition of AMPK but not of CaMKIalpha. | 27151216 |
| 2015-10-03 10:45:00 | CaMKKalpha and CaMKKbeta are capable of phosphorylating and activating CaMKIV in living cells. | 26050738 |
| 2010-01-21 00:00:00 | Recombinant CaM-KK alpha exhibits a high calcium/calmodulin-dependent activity with a weak autonomous activity. | 11705382 |
| 2010-01-21 00:00:00 | Thr196 phosphorylation of CaM-KIV by CaM-KK reduces interaction of the catalytic core with the autoinhibitory region, resulting in generation of the autonomous activity | 15262966 |
| 2010-01-21 00:00:00 | ERK activation and neurite outgrowth in response to depolarization are mediated by CaMKK activation of CaMKI | 15150258 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
KKCC1_RAT,
F1LQD2_RAT
UniprotKB:
P97756,
F1LQD2
UniParc:
UPI000019C0ED,
UPI000004A175
EMBL:
AC097114,
L42810,
CH473948,
AB023658,
S83194
Ensembl:
ENSRNOG00000018242
KO:
rno:60341
|
| Nucleutide sequences |
EMBL-CDS:
BAA75246.1,
AAC42070.1,
AAB46910.1,
EDM05132.1
Gene_ORFName:
rCG_35534
Ensembl_TRS:
ENSRNOT00000025009
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000025009
RefSeq:
XP_008766088.1,
XP_006246861.1,
NP_113850.1,
XP_006246863.1
|
| Others |
UniRef100:
UniRef100_F1LQD2,
UniRef100_P97756
UniRef90:
UniRef90_P97756
UniRef50:
UniRef50_P97756
UniGene:
Rn.4851
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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