| Type | Description |
|---|---|
| Definition | BCL2 related protein A1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:12:00 | A redox switch regulates the structure and function of anti-apoptotic BFL-1. | 32661419 |
| 2020-07-25 11:23:00 | BFL1 inhibits apoptosis through three distinct mechanisms which are similar but not identical to those of BCLXL, the paradigmatic antiapoptotic BCL2 family protein. | 30560933 |
| 2020-07-11 12:57:00 | prenylated Rab acceptor 1 (RABAC1 or PRA1) inhibits the anti-apoptotic activity of BCL2A1 and induces apoptosis in AGS gastric cancer cells. | 31003775 |
| 2020-07-11 12:08:00 | overexpression of TRIM28 or knock-out of TRIM17 reduced BCLA1 protein levels and restored sensitivity of melanoma cells to BRAF-targeted therapy. Therefore, our data describe a molecular rheostat in which two proteins of the TRIM family antagonistically regulate BCL2A1 stability and modulate cell death. | 30042493 |
| 2020-07-04 12:24:00 | Comparative transcriptome analysisuncovered BCL2A1 as a potential mediator of ABT-199 resistance in acute myeloid leukemias | 31300747 |
| Type | IDs |
|---|---|
| Synonymous | ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1 |
| Gene |
UniProtKB-ID:
B2LA1_HUMAN
UniprotKB:
Q16548
UniParc:
UPI00001268AE,
UPI00001867D4
EMBL:
CR541937,
U29680,
CR541962,
CH471136,
AC015871,
AY234180,
Y09397,
U27467,
BC016281,
BT007103
Ensembl:
ENSG00000140379
KO:
hsa:597
|
| Nucleutide sequences |
EMBL-CDS:
AAO89009.1,
EAW99129.1,
AAP35767.1,
CAG46735.1,
AAH16281.1,
AAC50438.1,
AAC50288.1,
CAG46760.1,
CAA70566.1
Ensembl_TRS:
ENST00000335661,
ENST00000267953
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000335250,
ENSP00000267953
RefSeq:
NP_001108207.1,
NP_004040.1
|
| Others |
UniRef100:
UniRef100_Q16548
UniRef90:
UniRef90_Q16548
UniRef50:
UniRef50_Q16548
UniGene:
Hs.227817
CCDS:
CCDS10312.1,
CCDS45322.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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