| Type | Description |
|---|---|
| Definition | dynein light chain LC8-type 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 10:15:00 | It has been found that APC2 localizes as distinct clusters along microtubule bundles in dendrites, and that this localization is driven by LC8-binding and two separate microtubule-interacting domains. | 30018294 |
| 2016-04-30 11:30:00 | silencing of Dynein light chain LC8 or class I transcription factor A2 resulted in a loss of CITFA from RNA Pol I promoters | 26459761 |
| 2014-11-22 12:34:00 | Data suggest that redox-sensitive and protein inhibitor of nNOS (PIN)-mediated neuronal NO synthase (nNOS) uncoupling is engaged in a vicious cycle that sustains the production of reactive oxygen species in rostral ventrolateral medulla (RVLM). | 24958506 |
| 2014-10-25 11:02:00 | results suggest that PIN is involved in the development of hypertension. | 24035314 |
| 2013-11-16 11:52:00 | Our results show a novel intermediary mechanism that leads to decreased levels of active nNOS in the PVN, involved in subsequent reduction in sympathoinhibition during CHF, offering a new target for the treatment of CHF and other cardiovascular diseases. | 23832698 |
| Type | IDs |
|---|---|
| Synonymous | 8kDLC, Dlc8, Dnclc1, Pin |
| Gene |
UniProtKB-ID:
DYL1_RAT
UniprotKB:
P63170
UniParc:
UPI0000000991
EMBL:
U66461,
BC063183
Ensembl:
ENSRNOG00000011222
KO:
rno:58945
|
| Nucleutide sequences |
EMBL-CDS:
AAB38257.1,
AAH63183.1
Ensembl_TRS:
ENSRNOT00000014910
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000061342
RefSeq:
NP_445771.1
|
| Others |
UniRef100:
UniRef100_P63167
UniRef90:
UniRef90_P63167
UniRef50:
UniRef50_P63167
UniGene:
Rn.35769
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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