| Type | Description |
|---|---|
| Definition | RAB13, member RAS oncogene family |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:37:00 | GGA2 and RAB13 are important specificity determinants for integrin activity-dependent traffic. | 31076515 |
| 2020-05-30 12:15:00 | The deletion of RAB13 inhibited the proliferation and promoted the apoptosis in AGS and NCI-N87cells, the impairments of viability which was due to reduced amount of RAB13 anchoring the plasma membrane and attenuated cellular response to EGF treatment and the activation of downstream Akt/ERK/mTOR signaling pathways accordingly. | 31474334 |
| 2017-10-07 12:51:00 | Rab13 activated the downstream AMPK and blocked mTOR signaling by its functional interaction with Grb2 to regulate autophagy in human vascular endothelial cells. | 28087344 |
| 2016-12-17 11:23:00 | Inactive Rab13 appears to associate with vesicles via protein-protein interactions. Only following activation does Rab13 associate with the plasma membrane, presumably with insertion of the C-terminal prenyl group into the membrane. | 26969162 |
| 2016-11-12 11:50:00 | the role of Rab13 as a potent driver of cancer progression. | 27044746 |
| Type | IDs |
|---|---|
| Synonymous | GIG4 |
| Gene |
UniProtKB-ID:
RAB13_HUMAN,
Q504R6_HUMAN,
A0A087WWB9_HUMAN
UniprotKB:
P51153,
Q504R6,
A0A087WWB9
UniParc:
UPI0001B38078,
UPI000050D03E,
UPI0000001264
EMBL:
BC073168,
X75593,
BT019700,
AF498948,
BC000799,
CH471121,
AL358472,
BC009227,
AK291580,
BC094846,
BT019701,
AY423722
Ensembl:
ENSG00000143545
KO:
hsa:5872
|
| Nucleutide sequences |
EMBL-CDS:
AAH00799.1,
AAV38506.1,
AAH09227.2,
AAH73168.2,
AAS00485.1,
BAF84269.1,
EAW53250.1,
EAW53249.1,
AAM21096.1,
CAA53266.1,
AAV38507.1,
AAH94846.1
Gene_ORFName:
GIG4
Ensembl_TRS:
ENST00000368575,
ENST00000614713
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357564,
ENSP00000480103
RefSeq:
NP_001258967.1,
NP_002861.1,
XP_016857448.1
|
| Others |
UniRef100:
UniRef100_P51153
UniRef90:
UniRef90_P51153
UniRef50:
UniRef50_P51153
UniGene:
Hs.151536
CCDS:
CCDS1058.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员