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5800 PTPRO

5800

PTPRO

protein tyrosine phosphatase receptor type O

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein tyrosine phosphatase receptor type O

研究结论

Date Results Publications
2021-03-20 13:31:00 IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma. 32581055
2020-09-19 16:29:00 LncRNA HULC promotes lung squamous cell carcinoma by regulating PTPRO via NF-kappaB. 31448453
2020-05-23 11:03:00 PTPRO was significantly upregulated and negatively associated with miR-548c-5p in placental mononuclear cells in patients with preeclampsia. 30443949
2018-03-31 11:55:00 the present study demonstrated that PTPRO inhibits tumor growth in vitro and in vivo, indicating the tumor suppressive function of PTPRO in LSCC. This study highlights PTPRO as an epigenetically silenced gene, and a candidate tumor-suppressor of LSCC. 28586036
2017-12-16 11:32:00 Single nucleotide polymorphism in PTPRO gene is associated with Acute Renal Graft Rejection. 27272414

名称对应

Type IDs
Synonymous GLEPP1, NPHS6, PTP-OC, PTP-U2, PTPROT, PTPU2, R-PTP-O
Gene
UniProtKB-ID: PTPRO_HUMAN, A0A024RAS0_HUMAN, A0A024RAS9_HUMAN
UniprotKB: Q16827, A0A024RAS0, A0A024RAS9
UniParc: UPI000013DC62, UPI000004DC16, UPI00000713D1, UPI000007175F, UPI0000074262
EMBL: AK290982, BC126203, U20489, AC007542, BC035960, AC022334, Z48541, AF187044, AC092183, AF187043, BC126201, CH471094
Ensembl: ENSG00000151490
KO: hsa:5800
Nucleutide sequences
EMBL-CDS: EAW96351.1, AAF04087.1, EAW96349.1, CAA88425.1, AAI26202.1, BAF83671.1, AAF04086.1, EAW96350.1, AAI26204.1, AAA82892.1, AAH35960.1, EAW96353.1, EAW96352.1
Gene_ORFName: hCG_25166, hCG_25166
Ensembl_TRS: ENST00000542557, ENST00000544244, ENST00000281171, ENST00000674316, ENST00000348962, ENST00000442921, ENST00000543886, ENST00000674261, ENST00000674388, ENST00000445537
Protein sequencees
Ensembl_PRO: ENSP00000444173, ENSP00000501352, ENSP00000437571, ENSP00000393449, ENSP00000439234, ENSP00000343434, ENSP00000501538, ENSP00000404188, ENSP00000281171, ENSP00000501494
RefSeq: NP_002839.1, XP_016875214.1, NP_109595.1, NP_109596.1, NP_109592.1, NP_109593.1, NP_109594.1
Others
UniRef100: UniRef100_Q16827, UniRef100_A0A024RAS0
UniRef90: UniRef90_Q16827
UniRef50: UniRef50_Q16827
UniGene: Hs.160871
CCDS: CCDS44837.1, CCDS53754.1, CCDS8675.1, CCDS8674.1

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研究热度

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