| Type | Description |
|---|---|
| Definition | SLIT-ROBO Rho GTPase activating protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-30 12:38:00 | the RhoA antagonist, SRGAP1, is present at subconfluent junctions to a greater extent than in confluent cultures and SRGAP1 restores RhoA signaling and contractility in subconfluent cultures to levels seen in confluent cells. | 29160905 |
| 2019-03-09 11:40:00 | High SRGAP1 expression is associated with gastric tumorigenesis. | 29234151 |
| 2017-12-16 11:23:00 | Results show that the protein expression of srGAP1 is remarkably decreased in 47.5% of colorectal cancer (CRC) tissues compared and is found to be associated with tumor progression and poor prognosis. | 27923383 |
| 2016-03-12 10:34:00 | we identified a consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P(meta) = 1.14 x 10(-7)) | 25134534 |
| 2015-09-26 10:35:00 | Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract | 26026792 |
| Type | IDs |
|---|---|
| Synonymous | ARHGAP13, NMTC2 |
| Gene |
UniProtKB-ID:
SRGP1_HUMAN
UniprotKB:
Q7Z6B7
UniParc:
UPI00001A9CB9,
UPI0000376ABB
EMBL:
BC053903,
AB037725
Ensembl:
ENSG00000196935
KO:
hsa:57522
|
| Nucleutide sequences |
EMBL-CDS:
AAH53903.1,
BAA92542.1
Ensembl_TRS:
ENST00000355086
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000347198
RefSeq:
XP_024304864.1,
XP_011536883.1,
XP_024304865.1,
NP_065813.1,
NP_001333130.1,
XP_011536882.1
|
| Others |
UniRef100:
UniRef100_Q7Z6B7
UniRef90:
UniRef90_Q7Z6B7
UniRef50:
UniRef50_Q7Z6B7
UniGene:
Hs.210751,
Hs.593803
CCDS:
CCDS8967.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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