| Type | Description |
|---|---|
| Definition | adhesion G protein-coupled receptor B1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:14:00 | EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway. | 31582835 |
| 2020-09-12 16:06:00 | Brain-specific angiogenesis inhibitor 1 is expressed in the Myo/Nog cell lineage. | 32614850 |
| 2019-05-25 11:46:00 | Brain-specific angiogenesis inhibitor 1 (BAI1) prevents proto-oncogene Protein c-mdm2 (Mdm2)-mediated tumor supressor p53 (p53) polyubiquitination, and its loss substantially reduces p53 levels. | 29894688 |
| 2018-02-10 12:03:00 | We have uncovered a new role for BAI1 in facilitating macrophage anti-viral responses. We show that arming oHSV with antiangiogenic Vstat120 also shields them from inflammatory macrophage antiviral response, without reducing safety | 27852701 |
| 2016-07-16 11:05:00 | Data suggest agonist-induced signal transduction via either BAI1/ADGRB1 or GPR56/ADGRG1 does not require conserved membrane-proximal stalk region; thus, it appears GAIN domain cleavage via autoproteolysis is not necessary for receptor activation. | 26710850 |
| Type | IDs |
|---|---|
| Synonymous | BAI1, GDAIF |
| Gene |
UniProtKB-ID:
AGRB1_HUMAN
UniprotKB:
O14514
UniParc:
UPI00002109E8
EMBL:
AC139676,
AB005297
Ensembl:
ENSG00000181790
KO:
hsa:575
|
| Nucleutide sequences |
EMBL-CDS:
BAA23647.1
Ensembl_TRS:
ENST00000323289,
ENST00000517894
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000430945,
ENSP00000313046
RefSeq:
XP_016869181.1,
XP_016869183.1,
XP_016869182.1,
NP_001693.2,
XP_011515504.1,
XP_016869185.1,
XP_016869186.1,
XP_016869180.1,
XP_016869184.1
|
| Others |
UniRef100:
UniRef100_O14514
UniRef90:
UniRef90_O14514
UniRef50:
UniRef50_O14514
UniGene:
Hs.194654
CCDS:
CCDS64985.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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