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57125 PLXDC1

57125

PLXDC1

plexin domain containing 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition plexin domain containing 1

研究结论

Date Results Publications
2020-04-18 11:35:00 Serum TEM5 and TEM7 concentrations correlate with clinicopathologic features and poor prognosis of colorectal cancer patients 31352222
2019-06-08 11:05:00 Study revealed that over-expression of PLXDC1 per se was able to change partly the growth features of U87MG glioblastoma cells. Molecularly, PLXDC1 regulated the epithelial to mesenchymal transition program of tumor cells, whereby its silencing increased the mRNA levels of epithelial transcripts, whereas those of mesenchymal marker genes were reduced. 30414187
2018-10-20 10:27:00 PLXDC1 silencing by the HA-CH-NP/siRNA significantly inhibited tumor growth in A2780 tumor-bearing mice. 29890852
2016-08-06 11:47:00 Immunohistochemical analysis of 122 gliomas showed that TGLI1 expression was positively correlated with VEGF-C, TEM7 and microvessel density. 26093087
2015-09-12 10:07:00 PLXDC1 and PLXDC2 as the transmembrane receptors for the multifunctional factor PEDF. 25535841

名称对应

Type IDs
Synonymous TEM3, TEM7
Gene
UniProtKB-ID: PLDX1_HUMAN
UniprotKB: Q8IUK5
UniParc: UPI000049801E, UPI0000489C7C, UPI0000D4FE78, UPI0000049814
EMBL: BC036059, AK312999, AY704670, AY704672, AY704671, AF279144, AF378753
Ensembl: ENSG00000161381
KO: hsa:57125
Nucleutide sequences
EMBL-CDS: BAG35835.1, AAV85657.1, AAL11990.1, AAV85658.1, AAH36059.1, AAG00869.2, AAV85659.1
Ensembl_TRS: ENST00000315392, ENST00000578390
Protein sequencees
Ensembl_PRO: ENSP00000323927, ENSP00000462089
RefSeq: NP_065138.2
Others
UniRef100: UniRef100_Q8IUK5
UniRef90: UniRef90_Q8IUK5
UniRef50: UniRef50_Q8IUK5
UniGene: Hs.125036
CCDS: CCDS11333.1

全选

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