| Type | Description |
|---|---|
| Definition | phospholipid scramblase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-20 11:20:00 | Specific DNA methylation signatures for aggressive choroid plexus carcinoma (CPC) revealed AK1, PER2, and PLSCR4 as potential biomarkers for CPC that can be used to improve molecular stratification for diagnosis and treatment. | 31409384 |
| 2020-03-28 10:54:00 | LINC00641 suppressed cell proliferation and induced cell apoptosis in NSCLC, indicating that LINC00641 exerted tumor-suppressive role in NSCLC. Through mechanism investigation, we determined that LINC00641 acted as a competing endogenous RNA (ceRNA) in NSCLC by sponging miR-424-5p to upregulate phospholipid scramblase (PLSCR4) expression. | 31322545 |
| 2017-01-28 11:41:00 | the first report on the transcriptional regulation of hPLSCR4, where Snail was shown to downregulate the expression of Human phospholipid scramblase 4 | 27363667 |
| 2013-04-06 10:48:00 | biochemical and functional characterization of human phospholipid scramblase 4 | 23089641 |
| 2012-05-12 11:51:00 | Crystallographic analysis of mammalian importin alpha1 in complex with the hPLSCR4-NLS reveals this minimal NLS binds specifically and exclusively to the minor binding site of importin alpha | 21690087 |
| Type | IDs |
|---|---|
| Synonymous | TRA1 |
| Gene |
UniProtKB-ID:
PLS4_HUMAN,
E9PHR9_HUMAN
UniprotKB:
Q9NRQ2,
E9PHR9
UniParc:
UPI000004182E,
UPI0001761705,
UPI00001C0FEE
EMBL:
AY550971,
AL833760,
AF087887,
BC028354,
AK128442,
AK290214,
CH471052,
AF199023,
AC092982
Ensembl:
ENSG00000114698
KO:
hsa:57088
|
| Nucleutide sequences |
EMBL-CDS:
AAT52217.1,
AAP97186.1,
CAH56232.1,
BAF82903.1,
BAC87442.1,
AAF89960.1,
EAW78935.1,
AAH28354.1
Gene_ORFName:
GIG43
Ensembl_TRS:
ENST00000446574,
ENST00000354952,
ENST00000493382,
ENST00000433593,
ENST00000383083
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000419040,
ENSP00000399315,
ENSP00000415605,
ENSP00000347038,
ENSP00000372561
RefSeq:
XP_024309455.1,
NP_001121776.1,
XP_011511333.1,
XP_005247711.1,
NP_001121777.1,
NP_001121778.1,
NP_001170775.1,
XP_016862410.1,
XP_024309454.1,
XP_005247712.1,
NP_065086.2
|
| Others |
UniRef100:
UniRef100_E9PHR9,
UniRef100_Q9NRQ2
UniRef90:
UniRef90_E9PHR9,
UniRef90_Q9NRQ2
UniRef50:
UniRef50_E9PHR9,
UniRef50_Q9NRQ2
UniGene:
Hs.477869
CCDS:
CCDS3133.1,
CCDS54651.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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