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56965 PARP6

56965

PARP6

poly(ADP-ribose) polymerase family member 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition poly(ADP-ribose) polymerase family member 6

研究结论

Date Results Publications
2017-04-22 12:18:00 Results showed that both and survivin exhibited higher expression in colorectal adenocarcinoma tissues and cell lines. knockdown of either Pduanyu376 or survivin promotes cell apoptosis and inhibits the cell invasion of colorectal adenocarcinoma cells suggesting a significant correlation between theses 2 proteins. 28260087
2017-02-04 11:57:00 acts as a tumor suppressor via downregulating Survivin expression in CRC. Pduanyu376 can be a novel diagnostic and therapeutic target together with Survivin for CRC. 26934315
2013-04-20 13:54:00 a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development, colorectal cancer had a good prognosis. 23042038
2010-06-30 22:07:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous ARTD17, PARP-6-B1, PARP-6-C, pART17
Gene
UniProtKB-ID: PARP6_HUMAN, A0A024R5Z4_HUMAN
UniprotKB: Q2NL67, A0A024R5Z4
UniParc: UPI0000E02139, UPI000067DA73, UPI0000E0213B
EMBL: AL390093, AK022547, CH471082, AL122091, AK024703, AK021790, BC110902
Ensembl: ENSG00000137817
KO: hsa:56965
Nucleutide sequences
EMBL-CDS: CAB59261.1, BAB14969.1, CAB98250.1, BAB13896.1, BAB14092.1, AAI10903.1, EAW77891.1, EAW77895.1, EAW77896.1
Gene_ORFName: hCG_40464
Ensembl_TRS: ENST00000569795, ENST00000287196, ENST00000260376
Protein sequencees
Ensembl_PRO: ENSP00000260376, ENSP00000456348, ENSP00000287196
RefSeq: XP_011520107.1, NP_001310455.1, NP_064599.2, NP_001310460.1, NP_001310459.1, NP_001310457.1, NP_001310448.1, NP_001310450.1, NP_001310461.1, XP_024305765.1, NP_001310454.1, NP_001310445.1, NP_001310453.1, XP_024305764.1, XP_016877907.1, NP_001310452.1, NP_001310451.1, XP_024305766.1, XP_024305763.1, NP_001310444.1
Others
UniRef100: UniRef100_Q2NL67
UniRef90: UniRef90_Q2NL67
UniRef50: UniRef50_Q2NL67
UniGene: Hs.270244
CCDS: CCDS10241.2

全选

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