| Type | Description |
|---|---|
| Definition | neuromedin U receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 12:58:00 | Activation by NMU2 is longer lasting if NmS is the ligand. | 29724789 |
| 2018-03-31 10:16:00 | NMU might contribute to progression of NMUR2-positive breast cancer | 28423716 |
| 2016-08-20 11:29:00 | polymorphisms in the gene may be useful in identifying women at risk for osteoporosis. | 25871004 |
| 2016-05-28 12:16:00 | Study identified a novel NMUR2 splice variant lacking the third exon and able to form heteromeric complexes with NMUR1 and NMUR2 without Neuromedin U (NMU). Its expression can block NMU signaling suppressing then ovarian cancer cells proliferation. | 26317338 |
| 2010-01-21 00:00:00 | A cell-based reporter gene assay has been developed and used for the screening of the human NMU2R agonist. | 16781063 |
| Type | IDs |
|---|---|
| Synonymous | FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1 |
| Gene |
UniProtKB-ID:
NMUR2_HUMAN
UniprotKB:
Q9GZQ4
UniParc:
UPI000013CE9D
EMBL:
AF272363,
AF242874,
BC067776,
AC008571,
AF292402,
BC016938,
AB041228
Ensembl:
ENSG00000132911
KO:
hsa:56923
|
| Nucleutide sequences |
EMBL-CDS:
BAB13721.1,
AAF82755.1,
AAH16938.1,
AAG24794.1,
AAH67776.1,
AAG03064.1
Ensembl_TRS:
ENST00000255262
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000255262
RefSeq:
XP_011535972.1,
NP_064552.3
|
| Others |
UniRef100:
UniRef100_Q9GZQ4
UniRef90:
UniRef90_Q9GZQ4
UniRef50:
UniRef50_Q9GZQ4
UniGene:
Hs.731911
CCDS:
CCDS4321.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 29724789 |
Ligand-Specific Signaling Profiles and Resensitization Mechanisms of the Neuromedin U2 Receptor. Mol. Pharmacol. Khaled Alhosaini , Omar Bahattab , Heider Qassam , R A John Challiss , Gary B Willars |
2018-07-01 | - |
| 28423716 |
Oncotarget Stefan Garczyk , Natalie Klotz , Sabrina Szczepanski , Bernd Denecke , Wiebke Antonopoulos , Saskia von Stillfried , Ruth Knüchel , Michael Rose , Edgar Dahl |
2017-05-30 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 25871004 |
Polymorphisms in neuropeptide genes and bone mineral density in Korean postmenopausal women. Menopause Eun Hee Chun , Hoon Kim , Chang Suk Suh , Jong Hak Kim , Dong Yeon Kim , Jung Gu Kim |
2015-11-01 | - |
| 26317338 |
PLoS ONE Ting-Yu Lin , Wei-Lin Huang , Wei-Yu Lee , Ching-Wei Luo |
2015-01-01 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 24024966 |
Genome-wide association study of chronic periodontitis in a general German population. J. Clin. Periodontol. Alexander Teumer , Birte Holtfreter , Uwe Völker , Astrid Petersmann , Matthias Nauck , Reiner Biffar , Henry Völzke , Heyo K Kroemer , Peter Meisel , Georg Homuth , Thomas Kocher |
2013-11-01 |
PDCD6IP,
ST20-MTHFS,
CDH13,
LOC101927025,
LOC101927661,
LOC101928114,
LOC101928134,
LOC102724761,
MTHFS,
CHD1,
PTPRT,
GPN1,
C1orf87,
WDR36,
NRSN1,
PSMA8,
ZNF524,
CCDC13,
NKAIN2,
FAM47A,
ZNF579,
PARP15,
DEFA1,
C10orf91,
ADAMTS15,
ABCA1,
EPHA3,
ETS2,
NLGN1,
DKK1,
KDM4B,
NPAP1,
FRG1,
ERC2,
DAOA,
LINC00907,
SUMF1,
NKAIN3,
GRIK1,
LRP12,
HLA-DOA,
FOXA1,
BIRC5,
C12orf74,
HMX3,
IGF2R,
IGL,
KCNJ16,
FAM180A,
LBP,
ST20,
LOC400867,
NPM1P2,
FAM135B,
PIK3C3,
LRP1B,
ETAA1,
RBFOX1,
PGPEP1,
ETNK2,
NMUR2,
RGMA,
ERGIC1,
PTEN,
SEMA6A,
RIT2,
ROBO2,
RYR3,
BCORL1,
SCN2A,
BLK,
SETMAR,
CSMD1,
MFSD1,
SMURF2,
PRB2,
SNRPN,
SNTB1,
SS18,
TGIF1,
TIMP2,
ROCK1P1,
VPREB1,
ZNF385D,
THSD4,
CAMK4,
LINC00208,
RAB6C,
FAM126A,
FIZ1,
WDR73,
ITGA8,
ACTN1,
ACTN2,
MBD2,
HS6ST2,
IQSEC1
|
| 22688191 |
Mol. Psychiatry S E Bergen , C T O'Dushlaine , S Ripke , P H Lee , D M Ruderfer , S Akterin , J L Moran , K D Chambert , R E Handsaker , L Backlund , U Ãsby , S McCarroll , M Landen , E M Scolnick , P K E Magnusson , P Lichtenstein , C M Hultman , S M Purcell , P Sklar , P F Sullivan |
2012-09-01 |
GPR1-AS,
LINC01470,
KCNMB2,
DLC1,
SPTLC1,
AGAP1,
CMKLR1,
DPYD,
NT5C2,
GPR1,
ANK3,
SNX8,
MRM2,
HLA-E,
IRF2BP2,
LINC00243,
HCG23,
MMP16,
MSRA,
NUDT1,
ROR2,
COMMD10,
CNNM2,
NMUR2,
ZDBF2,
ZSWIM6,
PTBP2,
PKNOX2,
CSMD1,
TCF4,
CACNA1C,
MAD1L1,
NLRC5,
ADAM23,
FEZ1
|
| 20395239 |
Genome-wide association identifies ATOH7 as a major gene determining human optic disc size. Hum Mol Genet Stuart Macgregor , Alex W Hewitt , Pirro G Hysi , Jonathan B Ruddle , Sarah E Medland , Anjali K Henders , Scott D Gordon , Toby Andrew , Brian McEvoy , Paul G Sanfilippo , Francis Carbonaro , Vikas Tah , Yi Ju Li , Sonya L Bennett , Jamie E Craig , Grant W Montgomery , Khanh-Nhat Tran-Viet , Nadean L Brown , Timothy D Spector , Nicholas G Martin , Terri L Young , Christopher J Hammond , David A Mackey |
2010-07-01 | - |
| 18577758 |
Dissociation of heterotrimeric g proteins in cells. Sci Signal Nevin A Lambert |
2008-01-01 |
INSL5,
LPAR6,
RAMP2,
RAMP3,
NMUR1,
CXCL13,
CXCR6,
GNA13,
CCR9,
CCL27,
UTS2,
PTGDR2,
HRH3,
CHRM1,
CHRM2,
CHRM4,
GNRHR2,
ADCYAP1R1,
CCR1,
CCR3,
CCR4,
CCR5,
CCR6,
CCR7,
CCR8,
CNR1,
CNR2,
ADORA1,
TAAR1,
CRHR1,
CRHR2,
ADORA3,
ADRA1B,
ADRA2A,
GPBAR1,
ADRA2C,
OXER1,
DRD2,
DRD3,
DRD4,
AGTR1,
AGTR2,
APLNR,
S1PR1,
LPAR1,
S1PR3,
EDN3,
EDNRA,
EDNRB,
F2R,
FPR1,
FPR3,
FSHR,
GAST,
NPB,
GALR1,
GCG,
GHRHR,
GIPR,
P2RY10,
GLP1R,
GNAI1,
GNAI2,
GNAI3,
GNAQ,
GNB1,
CCR10,
NPBWR1,
NPBWR2,
NPW,
GPR18,
MCHR1,
CXCL1,
CXCL2,
CXCL3,
HRH1,
HTR1A,
HTR1B,
HTR1D,
HTR1E,
HTR1F,
HTR2A,
HTR4,
HTR5A,
HTR6,
HTR7,
IAPP,
RXFP4,
CXCL8,
CXCR1,
CXCR2,
LHCGR,
MC3R,
MLN,
MTNR1A,
MTNR1B,
NPY,
NPY1R,
NPY2R
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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