| Type | Description |
|---|---|
| Definition | signal peptide, CUB domain, EGF-like 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-05-26 11:54:00 | Importantly, Scube2 uncouples processing of Shh peptides from their lipid-mediated juxtamembrane positioning, and thereby explains the long-standing conundrum that N-terminally unlipidated Shh shows patterning activity in Scube2-expressing vertebrates. | 28778988 |
| 2017-06-24 10:56:00 | Endothelial SCUBE2 may be a novel coreceptor for VEGFR2 and potentiate VEGF-induced signaling in adult angiogenesis. | 27834687 |
| 2016-03-26 11:25:00 | Scube2 plays a key regulatory role in Ihh-dependent endochondral bone formation. | 25639508 |
| 2012-09-01 11:06:00 | The role of Scube/You proteins in Hh signaling in vivo is to facilitate the release and mobilization of Hh proteins for distant action. | 22677548 |
| 2012-01-14 10:23:00 | Scube2 may play an important role during development of multiple regions in the embryo. | 21822616 |
| Type | IDs |
|---|---|
| Synonymous | 4932442O19Rik, Cegf1, Cegp1 |
| Gene |
UniProtKB-ID:
D3YVM9_MOUSE
UniprotKB:
D3YVM9
UniParc:
UPI0000F2237A
EMBL:
AC165959,
AC132584
Ensembl:
ENSMUSG00000007279
KO:
mmu:56788
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000106729
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000102340
RefSeq:
NP_064436.2
|
| Others |
UniRef100:
UniRef100_D3YVM9
UniRef90:
UniRef90_Q9JJS0
UniRef50:
UniRef50_Q9JJS0
UniGene:
Mm.40447
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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