| Type | Description |
|---|---|
| Definition | actin related protein 2/3 complex, subunit 3 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 12:16:00 | This study provided the first evidence that the Arp2/3 complex, a key actin nucleator, is involved in distinct stages of spine formation and is required for synapse unsilencing. | 27629719 |
| 2016-03-12 10:25:00 | In the absence of ArpC3, enterocytes had defects in the organization of the endolysosomal system: transcytosis of IgG was disrupted, lipid absorption was perturbed, and neonatal mice died within days of birth. | 25833710 |
| 2014-02-08 10:53:00 | GMF debranches filaments by a mechanism related to cofilin-mediated severing, but in which GMF has evolved to target molecular junctions between actin-related proteins in the Arp2/3 complex and actin subunits in the daughter filament of the branch. | 23727094 |
| 2012-09-22 10:24:00 | Together with the observation that Gadkin-mediated inhibition of cell spreading requires its binding to these data indicate that Gadkin is a negative regulator of function present on intracellular membranes | 22689987 |
| 2012-06-09 11:23:00 | results demonstrate a critical role for the Arp2/3 complex in the assembly of lamellipodia-based leading edges and directional cell motility | 22492726 |
| Type | IDs |
|---|---|
| Synonymous | 1110006A04Rik, p21-ARC, p21-Ar, p21Arc |
| Gene |
UniProtKB-ID:
ARPC3_MOUSE
UniprotKB:
Q9JM76
UniParc:
UPI0000028E84
EMBL:
AK003485,
BC054440,
AB038243,
BC013618,
AK171651,
AK005437
Ensembl:
ENSMUSG00000029465
KO:
mmu:56378
|
| Nucleutide sequences |
EMBL-CDS:
BAB22813.1,
AAH13618.1,
BAE42588.1,
BAB24031.1,
BAA90788.1,
AAH54440.1
Ensembl_TRS:
ENSMUST00000102525
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099584
RefSeq:
NP_062798.1
|
| Others |
UniRef100:
UniRef100_Q9JM76
UniRef90:
UniRef90_Q9JM76
UniRef50:
UniRef50_Q9JM76
UniGene:
Mm.275942
CCDS:
CCDS19648.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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