| Type | Description |
|---|---|
| Definition | apoptosis antagonizing transcription factor |
| Date | Results | Publications |
|---|---|---|
| 2020-03-14 12:21:00 | High AATF expression is associated with neuroblastoma. | 31545418 |
| 2020-02-15 10:05:00 | Study in Aatf conditional knockout mice found that Aatf suppressed RNA:DNA hybrid formation and enabled DNA double strand break repair in vitro. Results suggest that Aatf is a regulator of primary cilia and a modulator of the DNA damage response, connecting two pathogenetic mechanisms in nephronophthisis and related ciliopathies. | 30770218 |
| 2019-11-09 11:53:00 | Che-1 alleviates hypoxia/re-oxygenation-induced cardiomyocyte apoptosis by up-regulation of Nrf2 signaling. | 29509260 |
| 2017-08-12 11:46:00 | we found that object recognition memory persistence at 7days was impaired in Che-1(+/-) heterozygous mice. This is the first evidence showing that Che-1 is involved in memory processes. | 27589891 |
| 2013-04-13 10:32:00 | These results identify AATF as a nucleolar-confined c-Jun cofactor whose expression levels and spatial distribution determine the stress-induced activity of c-Jun and the levels of c-Jun-mediated apoptosis. | 22933572 |
| Type | IDs |
|---|---|
| Synonymous | 4933415H02Rik, 5830465M17Rik, Che-1, Trb |
| Gene |
UniProtKB-ID:
AATF_MOUSE
UniprotKB:
Q9JKX4
UniParc:
UPI0000021620,
UPI00000E9C31,
UPI0000551C5A
EMBL:
AL603708,
AK077789,
AL672252,
AY306199,
AF322223,
BC025080,
AF222801
Ensembl:
ENSMUSG00000018697
KO:
mmu:56321
|
| Nucleutide sequences |
EMBL-CDS:
AAF26745.1,
AAH25080.1,
AAP73747.1,
AAK07639.1,
BAC37011.1
Ensembl_TRS:
ENSMUST00000018841
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000018841
RefSeq:
NP_062790.1,
XP_006533852.1,
XP_036012757.1
|
| Others |
UniRef100:
UniRef100_Q9JKX4
UniRef90:
UniRef90_Q9JKX4
UniRef50:
UniRef50_Q9JKX4
UniGene:
Mm.257482
CCDS:
CCDS25186.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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