例如:"NBL1", "4681", "drought"
收藏
5603 MAPK13

5603

MAPK13

mitogen-activated protein kinase 13

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitogen-activated protein kinase 13

研究结论

Date Results Publications
2020-08-29 12:46:00 MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer. 31695024
2019-10-26 10:14:00 p38delta promotes micro-aggregate transport by phosphorylating SQSTM1, a major scaffold protein that assembles soluble ubiquitylated proteins into micro-aggregates. 29930081
2019-05-25 10:20:00 Study identified p38alpha and p38delta as critical regulators of ASC oligomerization, inflammasome activation, and IL-1beta secretion in keratinocytes. Furthermore, data suggest that the nature of the mitogen-activated protein kinase regulating inflammasome activity exhibits a certain cell specificity, with p38 playing a predominant role in keratinocytes and Jun N-terminal kinase 1 in cells of myeloid origin. 29287762
2019-05-11 11:54:00 These observations indicate that p38alpha probably blocks brown adipose tissue thermogenesis through p38delta inhibition. 29979672
2019-03-30 12:04:00 Mitogen-activated protein kinases p38gamma/p38delta deficiency protects against Candida albicans infection by increasing reactive oxygen species and iNOS enzyme production and thus the antifungal capacity of neutrophils and macrophages. 29661910

名称对应

Type IDs
Synonymous MAPK 13, MAPK-13, PRKM13, SAPK4, p38delta
Gene
UniProtKB-ID: MK13_HUMAN, A0A024RD04_HUMAN
UniprotKB: O15264, A0A024RD04
UniParc: UPI00004560FE, UPI000012F182
EMBL: AF092535, BT007221, BC085196, AF100546, Z95152, U93232, KU178281, AF015256, CR536490, BC000433, BC001641, Y10488, BC004428, CH471081, AF004709
Ensembl: ENSG00000156711
KO: hsa:5603
Nucleutide sequences
EMBL-CDS: AAC51758.1, AAC51374.1, AAH85196.1, AAH00433.1, AAH01641.1, CAG38729.1, AAH04428.1, EAX03875.1, CAA71512.1, AAD23377.1, EAX03874.1, AAB87639.1, AAP35885.1, AAF36772.1, ALQ33739.1, EAX03876.1
Gene_ORFName: hCG_15774
Ensembl_TRS: ENST00000211287, ENST00000373766
Protein sequencees
Ensembl_PRO: ENSP00000362871, ENSP00000211287
RefSeq: XP_024302259.1, NP_002745.1
Others
UniRef100: UniRef100_O15264
UniRef90: UniRef90_O15264
UniRef50: UniRef50_O61443
UniGene: Hs.178695
CCDS: CCDS4818.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员