| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 12:22:00 | MAPK4 can promote cancer by activating the AKT/mTOR signaling pathway and that targeting MAPK4 may provide a novel therapeutic approach for cancer. | 30688659 |
| 2011-04-16 12:08:00 | Activation loop phosphorylation of ERK3/ERK4 by group I p21-activated kinases (PAKs) defines a novel PAK-ERK3/4-MAPK-activated protein kinase 5 signaling pathway. | 21177870 |
| 2010-01-21 00:00:00 | Data defined a novel MK5 interaction motif (FRIEDE) within both ERK4 and ERK3 that is essential for binding to the C-terminal region of MK5. | 19473979 |
| 2006-11-08 15:43:00 | Data show that in contrast to ERK3, ERK4 (MAPK4) is a stable protein and binds to Interaction of ERK4 with leads to translocation of MAduanyu1529PK-5 to the cytoplasm and to its activation by phosphorylation. ERK4 can form dimers with ERK3. | 16973613 |
| Type | IDs |
|---|---|
| Synonymous | ERK-4, ERK4, PRKM4, p63-MAPK, p63MAPK |
| Gene |
UniProtKB-ID:
MK04_HUMAN,
B4DEW2_HUMAN,
K7ELV1_HUMAN
UniprotKB:
P31152,
B4DEW2,
K7ELV1
UniParc:
UPI00017A6C71,
UPI00024D146E,
UPI0000201D20
EMBL:
AC090395,
AK293818,
AC090638,
AC012433,
BC117216,
CH471096,
AK295058,
BC050299,
X59727
Ensembl:
ENSG00000141639
KO:
hsa:5596
|
| Nucleutide sequences |
EMBL-CDS:
EAW62977.1,
EAW62976.1,
AAH50299.1,
CAA42411.1,
AAI17217.1,
BAG58107.1,
BAG57223.1
Ensembl_TRS:
ENST00000400384,
ENST00000540640,
ENST00000592595
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383234,
ENSP00000439231,
ENSP00000466233
RefSeq:
XP_011524380.1,
XP_011524379.1,
NP_002738.2,
XP_011524378.1,
XP_016881328.1,
XP_011524376.1,
XP_005258356.1,
XP_011524377.1,
NP_001278968.1,
NP_001278969.1
|
| Others |
UniRef100:
UniRef100_K7ELV1,
UniRef100_P31152
UniRef90:
UniRef90_P31152,
UniRef90_K7ELV1
UniRef50:
UniRef50_Q6P5G0,
UniRef50_Q63454
UniGene:
Hs.433728
CCDS:
CCDS42437.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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