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55951 Mpc1

55951

Mpc1

mitochondrial pyruvate carrier 1

protein-coding

Mus musculus

基因描述

Type Description
Definition mitochondrial pyruvate carrier 1

研究结论

Date Results Publications
2021-03-27 14:39:00 Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development. 32130894
2019-05-04 10:18:00 Retina-specific deletion of MPC1 results in progressive retinal degeneration and decline of visual function in both rod and cone photoreceptors. 30808746
2018-04-14 11:48:00 the MPC1 knockout blocks mitochondrial pyruvate uptake and OXPHOS, which results in metabolic reprogramming towards aerobic Warburg glycolysis with reduced ATP production capability. 28624784
2018-02-17 10:06:00 Heterozygous MPC1 KO weakens fertility and influences the metabolism of glucose and fatty acid and bodyweight in mice. 27835892
2017-12-30 11:05:00 This study suggests that inhibition of MPC1 activity can boost fatty acid oxidation to provide sufficient energy to the body. 29175325

名称对应

Type IDs
Synonymous 0610006G08Rik, 3830411I18Rik, Brp44l
Gene
UniProtKB-ID: MPC1_MOUSE, D3Z5S0_MOUSE, Q3UX28_MOUSE
UniprotKB: P63030, D3Z5S0, Q3UX28
UniParc: UPI0000028D7B, UPI00001EB303
EMBL: AK014421, BC024365, AC164431, AK135943, AK002241, BC103767, AF181116, AK002266, AK013391, AK004013
Ensembl: ENSMUSG00000023861
KO: mmu:55951
Nucleutide sequences
EMBL-CDS: AAF25816.1, BAB21976.1, BAB23124.1, BAB28826.1, BAB21958.1, BAB29340.1, AAH24365.1, AAI03768.1, BAE22735.1
Ensembl_TRS: ENSMUST00000155364, ENSMUST00000046754, ENSMUST00000130559
Protein sequencees
Ensembl_PRO: ENSMUSP00000045654, ENSMUSP00000119443, ENSMUSP00000116307
RefSeq: NP_001351848.1, NP_061289.1, XP_011244521.1, NP_001351847.1, XP_030105774.1
Others
UniRef100: UniRef100_P63030, UniRef100_D3Z5S0
UniRef90: UniRef90_D3Z5S0, UniRef90_P63030
UniRef50: UniRef50_P63030, UniRef50_M3Y4X6
UniGene: Mm.288510
CCDS: CCDS49944.1

全选

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研究热度

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