| Type | Description |
|---|---|
| Definition | solute carrier family 48 member 1 |
| Date | Results | Publications |
|---|---|---|
| 2014-11-22 13:37:00 | HRG-1 may represent a novel target for selectively disrupting V-ATPase activity and the metastatic potential of cancer cells. | 24141772 |
| 2013-09-21 12:29:00 | These results reveal HRG1 as the long-sought heme transporter for heme-iron recycling in macrophages and suggest that genetic variations in HRG1 could be modifiers of human iron metabolism. | 23395172 |
| 2012-04-21 12:02:00 | a model in which heme is translocated across membranes facilitated by conserved amino acids positioned on the exoplasmic, cytoplasmic, and transmembrane regions of HRG-1-related proteins. | 22174408 |
| 2011-09-14 12:13:00 | SLC48A1 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. | 21555518 |
| 2010-09-15 22:07:00 | Observational study of gene-disease association. (HuGE Navigator) | 19913121 |
| Type | IDs |
|---|---|
| Synonymous | HRG-1, HRG1, hHRG-1 |
| Gene |
UniProtKB-ID:
HRG1_HUMAN
UniprotKB:
Q6P1K1
UniParc:
UPI00001FC0AF,
UPI0000037770
EMBL:
CH471111,
BC002759,
AK000496,
BC026344,
BC065033
Ensembl:
ENSG00000211584
KO:
hsa:55652
|
| Nucleutide sequences |
EMBL-CDS:
AAH02759.2,
AAH65033.1,
AAH26344.2,
BAA91205.1,
EAW57951.1
Ensembl_TRS:
ENST00000442892,
ENST00000442218,
ENST00000547002
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000410134,
ENSP00000415998,
ENSP00000446739
RefSeq:
XP_016875103.1,
XP_005269073.1,
XP_016875101.1,
XP_016875106.1,
NP_060312.2,
XP_024304814.1,
XP_024304813.1
|
| Others |
UniRef100:
UniRef100_Q6P1K1
UniRef90:
UniRef90_Q6P1K1
UniRef50:
UniRef50_Q6P1K1
UniGene:
Hs.438867
CCDS:
CCDS8755.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 24141772 |
Oncogene F M Fogarty , J O'Keeffe , A Zhadanov , D Papkovsky , V Ayllon , R O'Connor |
2014-09-18 | - |
| 23395172 |
Cell Metab Carine White , Xiaojing Yuan , Paul J Schmidt , Erica Bresciani , Tamika K Samuel , Dean Campagna , Caitlin Hall , Kevin Bishop , Monica L Calicchio , Ariane Lapierre , Diane M Ward , Paul Liu , Mark D Fleming , Iqbal Hamza |
2013-02-05 | - |
| 23263486 |
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet Anna Köttgen , Eva Albrecht , Alexander Teumer , Veronique Vitart , Jan Krumsiek , Claudia Hundertmark , Giorgio Pistis , Daniela Ruggiero , Conall M O'Seaghdha , Toomas Haller , Qiong Yang , Toshiko Tanaka , Andrew D Johnson , Zoltán Kutalik , Albert V Smith , Julia Shi , Maksim Struchalin , Rita P S Middelberg , Morris J Brown , Angelo L Gaffo , Nicola Pirastu , Guo Li , Caroline Hayward , Tatijana Zemunik , Jennifer Huffman , Loic Yengo , Jing Hua Zhao , Ayse Demirkan , Mary F Feitosa , Xuan Liu , Giovanni Malerba , Lorna M Lopez , Pim van der Harst , Xinzhong Li , Marcus E Kleber , Andrew A Hicks , Ilja M Nolte , Asa Johansson , Federico Murgia , Sarah H Wild , Stephan J L Bakker , John F Peden , Abbas Dehghan , Maristella Steri , Albert Tenesa , Vasiliki Lagou , Perttu Salo , Massimo Mangino , Lynda M Rose , Terho Lehtimäki , Owen M Woodward , Yukinori Okada , Adrienne Tin , Christian Müller , Christopher Oldmeadow , Margus Putku , Darina Czamara , Peter Kraft , Laura Frogheri , Gian Andri Thun , Anne Grotevendt , Gauti Kjartan Gislason , Tamara B Harris , Lenore J Launer , Patrick McArdle , Alan R Shuldiner , Eric Boerwinkle , Josef Coresh , Helena Schmidt , Michael Schallert , Nicholas G Martin , Grant W Montgomery , Michiaki Kubo , Yusuke Nakamura , Toshihiro Tanaka , Patricia B Munroe , Nilesh J Samani , David R Jacobs , Kiang Liu , Pio D'Adamo , Sheila Ulivi , Jerome I Rotter , Bruce M Psaty , Peter Vollenweider , Gerard Waeber , Susan Campbell , Olivier Devuyst , Pau Navarro , Ivana Kolcic , Nicholas Hastie , Beverley Balkau , Philippe Froguel , Tõnu Esko , Andres Salumets , Kay Tee Khaw , Claudia Langenberg , Nicholas J Wareham , Aaron Isaacs , Aldi Kraja , Qunyuan Zhang , Philipp S Wild , Rodney J Scott , Elizabeth G Holliday , Elin Org , Margus Viigimaa , Stefania Bandinelli , Jeffrey E Metter , Antonio Lupo , Elisabetta Trabetti , Rossella Sorice , Angela Döring , Eva Lattka , Konstantin Strauch , Fabian Theis , Melanie Waldenberger , H-Erich Wichmann , Gail Davies , Alan J Gow , Marcel Bruinenberg , LifeLines Cohort Study , Ronald P Stolk , Jaspal S Kooner , Weihua Zhang , Bernhard R Winkelmann , Bernhard O Boehm , Susanne Lucae , Brenda W Penninx , Johannes H Smit , Gary Curhan , Poorva Mudgal , Robert M Plenge , Laura Portas , Ivana Persico , Mirna Kirin , James F Wilson , Irene Mateo Leach , Wiek H van Gilst , Anuj Goel , Halit Ongen , Albert Hofman , Fernando Rivadeneira , Andre G Uitterlinden , Medea Imboden , Arnold von Eckardstein , Francesco Cucca , Ramaiah Nagaraja , Maria Grazia Piras , Matthias Nauck , Claudia Schurmann , Kathrin Budde , Florian Ernst , Susan M Farrington , Evropi Theodoratou , Inga Prokopenko , Michael Stumvoll , Antti Jula , Markus Perola , Veikko Salomaa , So-Youn Shin , Tim D Spector , Cinzia Sala , Paul M Ridker , Mika Kähönen , Jorma Viikari , Christian Hengstenberg , Christopher P Nelson , CARDIoGRAM Consortium , DIAGRAM Consortium , ICBP Consortium , MAGIC Consortium , James F Meschia , Michael A Nalls , Pankaj Sharma , Andrew B Singleton , Naoyuki Kamatani , Tanja Zeller , Michel Burnier , John Attia , Maris Laan , Norman Klopp , Hans L Hillege , Stefan Kloiber , Hyon Choi , Mario Pirastu , Silvia Tore , Nicole M Probst-Hensch , Henry Völzke , Vilmundur Gudnason , Afshin Parsa , Reinhold Schmidt , John B Whitfield , Myriam Fornage , Paolo Gasparini , David S Siscovick , Ozren Polašek , Harry Campbell , Igor Rudan , Nabila Bouatia-Naji , Andres Metspalu , Ruth J F Loos , Cornelia M van Duijn , Ingrid B Borecki , Luigi Ferrucci , Giovanni Gambaro , Ian J Deary , Bruce H R Wolffenbuttel , John C Chambers , Winfried März , Peter P Pramstaller , Harold Snieder , Ulf Gyllensten , Alan F Wright , Gerjan Navis , Hugh Watkins , Jacqueline C M Witteman , Serena Sanna , Sabine Schipf , Malcolm G Dunlop , Anke Tönjes , Samuli Ripatti , Nicole Soranzo , Daniela Toniolo , Daniel I Chasman , Olli Raitakari , W H Linda Kao , Marina Ciullo , Caroline S Fox , Mark Caulfield , Murielle Bochud , Christian Gieger |
2013-02-01 | - |
| 22174408 |
Topologically conserved residues direct heme transport in HRG-1-related proteins. J Biol Chem Xiaojing Yuan , Olga Protchenko , Caroline C Philpott , Iqbal Hamza |
2012-02-10 | - |
| 21832049 |
J Biol Chem Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária Szũcs , Ferenc Orosz , Botond Penke , Judit Ovádi |
2011-09-30 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21555518 |
J. Biol. Chem. Hans-Jörg Warnatz , Dominic Schmidt , Thomas Manke , Ilaria Piccini , Marc Sultan , Tatiana Borodina , Daniela Balzereit , Wasco Wruck , Alexey Soldatov , Martin Vingron , Hans Lehrach , Marie-Laure Yaspo |
2011-07-01 |
BCL2L11,
CDK6,
COPS6,
SLX4IP,
SSC4D,
SLC25A10,
CTSL,
ADAMTS17,
AFG3L1P,
EWSR1,
FGF1,
ALDOA,
CLSTN1,
SLC7A11,
FTH1,
FTL,
RHBDD3,
GCLC,
GCLM,
GPI,
SLC9A9,
ANXA2P2,
HMOX1,
IFRD1,
ITPR2,
TMEM189,
TEX19,
MAFG,
MAPT,
ME1,
NQO2,
FAM49B,
MXRA8,
LRRC8D,
SLC48A1,
PSAP,
VTRNA1-2,
VTRNA1-1,
BACH1,
KIAA1549,
TTC23,
SMARCA4,
TFE3,
TKT,
TNFAIP2,
TNFRSF1A,
PHLDA2,
ZNF3,
CALM1,
ST8SIA2,
NPRL3,
TRIM56,
CFAP74,
SYNJ2,
SQSTM1,
BICDL1,
HTRA3,
SDC3,
SEMA3E,
NUP153
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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目前还没有研究热点人员