| Type | Description |
|---|---|
| Definition | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:23:00 | OTUB1 Is a Key Regulator of RIG-I-Dependent Immune Signaling and Is Targeted for Proteasomal Degradation by Influenza A NS1. | 32023470 |
| 2020-12-26 13:11:00 | Activation and selectivity of OTUB-1 and OTUB-2 deubiquitinylases. | 32265297 |
| 2020-09-12 10:56:00 | The Otub1 deficiency not only promotes signal-induced p100 processing and noncanonical NF-kappaB activation but also causes steady-state p100 degradation, leading to aberrant NF-kappaB activation in the canonical pathway. | 31086255 |
| 2020-08-12 10:39:00 | These findings suggest that OTUB1 is an important regulator of Nur77 stability and plays a role in controlling the inflammatory response. | 30905540 |
| 2019-12-14 10:27:00 | addition of FAT10 also led to an increased interaction between OTUB1 and its cognate E2 UbcH5B, implying a function of FAT10 in the inhibition of polyubiquitylation | 30718280 |
| Type | IDs |
|---|---|
| Synonymous | HSPC263, OTB1, OTU1 |
| Gene |
UniProtKB-ID:
OTUB1_HUMAN,
B3KUV5_HUMAN
UniprotKB:
Q96FW1,
B3KUV5
UniParc:
UPI000000D868,
UPI00003E60B6,
UPI000023FF0E
EMBL:
AK000120,
BC107701,
BC007519,
BC010368,
AY177200,
AK098029,
AF161381,
AP000721
Ensembl:
ENSG00000167770
KO:
hsa:55611
|
| Nucleutide sequences |
EMBL-CDS:
AAH07519.1,
AAF28941.1,
AAO27702.1,
BAA90956.1,
AAI07702.1,
AAH10368.1,
BAG53567.1
Gene_ORFName:
HSPC263
Ensembl_TRS:
ENST00000538426,
ENST00000428192
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000444357,
ENSP00000402551
RefSeq:
NP_060140.2
|
| Others |
UniRef100:
UniRef100_B3KUV5,
UniRef100_Q96FW1
UniRef90:
UniRef90_Q96FW1-2,
UniRef90_Q96FW1
UniRef50:
UniRef50_Q96FW1-2,
UniRef50_Q96FW1
UniGene:
Hs.473788
CCDS:
CCDS8055.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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