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55586 MIOX

55586

MIOX

myo-inositol oxygenase

protein-coding

Homo sapiens

基因描述

Type Description
Definition myo-inositol oxygenase

研究结论

Date Results Publications
2020-10-24 14:08:00 Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes. 32169892
2019-11-30 11:09:00 MIOX-induced oxidant stress and tunicamycin-induced endoplasmic reticulum stress are interlinked, and both of the events may feed into each other to amplify the tubulointerstitial injury. 30539651
2019-03-02 10:07:00 increased MIOX expression in the kidney contributes to tubular damage in DN (Diabetic Nephropathy). The concentration of MIOX in the serum and urine may serve as a new biomarker for the early diagnosis of DN. 30504713
2018-09-22 10:40:00 Our results suggest that serum MIOX levels do not change in polycystic ovary syndrome. It was, therefore, concluded that myoinositol deficiency observed in PCOS was not related to the level of MIOX enzyme which cleaves myoinositol. 29187000
2017-05-27 11:12:00 these findings highlight the epigenetic regulation of MIOX in the pathogenesis of diabetic tubulopathy. 28208054

名称对应

Type IDs
Synonymous ALDRL6
Gene
UniProtKB-ID: MIOX_HUMAN
UniprotKB: Q9UGB7
UniParc: UPI000012F148, UPI0000D493B6
EMBL: AY738258, AL096767, BC012025, CH471138, AY064416, AF230095, BC073848, AK000576, CR456478, AF197129
Ensembl: ENSG00000100253
KO: hsa:55586
Nucleutide sequences
EMBL-CDS: AAF25204.1, AAK00766.1, AAH73848.1, CAG30364.1, BAA91266.1, AAL47192.1, AAV65816.1, AAH12025.1, EAW73547.1
Ensembl_TRS: ENST00000395733, ENST00000216075
Protein sequencees
Ensembl_PRO: ENSP00000216075, ENSP00000379082
RefSeq: XP_011529007.1, XP_005261982.1, NP_060054.4
Others
UniRef100: UniRef100_Q9UGB7
UniRef90: UniRef90_Q9UGB7
UniRef50: UniRef50_Q9UGB7
UniGene: Hs.129227
CCDS: CCDS14092.1

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