| Type | Description |
|---|---|
| Definition | serglycin |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:29:00 | SRGN crosstalks with YAP to maintain chemoresistance and stemness in breast cancer cells by modulating HDAC2 expression. | 32292495 |
| 2020-12-19 13:41:00 | The role of SRGN in the survival and immune infiltrates of skin cutaneous melanoma (SKCM) and SKCM-metastasis patients. | 32370744 |
| 2020-06-06 12:28:00 | Proteoglycan SRGN promotes NSCLC cell migration via the binding of its GAG motif to CD44. SRGN/CD44 interaction induces Rho-family GTPase-mediated cytoskeleton reorganization and facilitates Src-mediated focal adhesion turnover, leading to increased cell migration. | 31898491 |
| 2020-02-29 10:52:00 | Serglycin is increased in human chondrocytes after interleukin-1beta stimulation. It binds CD44 receptor to amplify the inflammatory response. | 31145901 |
| 2020-02-15 10:09:00 | The current study suggests that increased maternal serum serglycin is associated with fetal growth restriction in early-onset preeclampsia. | 31018746 |
| Type | IDs |
|---|---|
| Synonymous | PPG, PRG, PRG1 |
| Gene |
UniProtKB-ID:
SRGN_HUMAN
UniprotKB:
P10124
UniParc:
UPI000013CB03
EMBL:
BC015516,
M90058,
AK311873,
M33649,
M33650,
AL442635,
M33651,
J03223,
X17042,
CH471083,
X12765
Ensembl:
ENSG00000122862
KO:
hsa:5552
|
| Nucleutide sequences |
EMBL-CDS:
CAA34900.1,
AAH15516.1,
EAW54309.1,
AAA60179.1,
BAG34814.1,
CAA31255.1,
AAA60322.1
Ensembl_TRS:
ENST00000242465
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000242465
RefSeq:
NP_001307983.1,
XP_024303833.1,
XP_024303834.1,
XP_024303832.1,
XP_016871881.1,
NP_002718.2,
NP_001307982.1
|
| Others |
UniRef100:
UniRef100_P10124
UniRef90:
UniRef90_P10124
UniRef50:
UniRef50_P10124
UniGene:
Hs.1908
CCDS:
CCDS7285.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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