| Type | Description |
|---|---|
| Definition | BRF2 RNA polymerase III transcription initiation factor subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-09-26 13:03:00 | MicroRNA-425-5p Inhibits Lung Growth in Vitro and in Vivo by Downregulating TFIIB-Related Factor 2. | 31964245 |
| 2020-05-23 10:52:00 | This study found a novel signaling pathway, namely MNX1-AS1/miR-527/BRF2 axis, involved in lung cancer progression. | 30618167 |
| 2018-10-27 11:27:00 | Results show that the mRNA and protein expression levels of BRF2 were markedly higher in non-small cell lung cancer (NSCLC) cells and highly related to differentiation degree, lymph node metastasis, clinical stage, and vascular invasion. miR-373 was identified to directly target BRF2, resulting in the enhanced migration and invasion of NSCLC A549 cells and indicating that BRF2 affects the metastasis of NSCLC. | 29025258 |
| 2018-10-20 12:08:00 | REVIEW: highlights the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations | 28854119 |
| 2017-11-18 13:49:00 | Data indicate the crystal structure of a Brf2-TBP-Bdp1 complex bound to a DNA promoter. | 28743884 |
| Type | IDs |
|---|---|
| Synonymous | BRFU, TFIIIB50 |
| Gene |
UniProtKB-ID:
BRF2_HUMAN
UniprotKB:
Q9HAW0
UniParc:
UPI000006D405,
UPI000206528F
EMBL:
AF130058,
AK315420,
CH471080,
AK294337,
AF298153,
BC010648,
AK001914,
AF206673
Ensembl:
ENSG00000104221
KO:
hsa:55290
|
| Nucleutide sequences |
EMBL-CDS:
EAW63351.1,
BAA91975.1,
AAG35669.2,
AAG35486.1,
BAG57607.1,
AAG30222.1,
EAW63352.1,
BAG37809.1,
EAW63353.1,
AAH10648.1
Gene_ORFName:
PRO1470
Ensembl_TRS:
ENST00000220659
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000220659
RefSeq:
NP_060780.2
|
| Others |
UniRef100:
UniRef100_Q9HAW0
UniRef90:
UniRef90_Q9HAW0
UniRef50:
UniRef50_Q9HAW0
UniGene:
Hs.709301
CCDS:
CCDS6098.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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