New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.

Transcription. 2018;9(1):61-66. doi:10.1080/21541264.2017.1335269. Epub 2017 Aug 30

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Here, we discuss the role of Brf2, an III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.

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New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer.

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