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55283 MCOLN3

55283

MCOLN3

mucolipin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition mucolipin 3

研究结论

Date Results Publications
2020-03-07 11:00:00 palmitoylation is a prerequisite for the function of MCOLN3/TRPML3 as a Ca(2+) channel in autophagosome formation. 30215288
2019-06-01 12:02:00 The work elucidates the molecular architecture and provides insights into how multiple ligands regulate TRPML1 and TRPML3. (Review) 29577631
2014-05-10 14:57:00 these results suggest that TRPML3 plays a role in autophagosome maturation through the interaction with GATE16, by providing Ca(2+) in the fusion process. 24269818
2013-08-31 12:09:00 TRPML3 and TRPV5 heteromers could have a biological function 23469151
2012-09-15 11:14:00 Negatively charged amino acids in the extracellular loops of TRPML3 may interfere with the observed sodium inhibition. 22753890

名称对应

Type IDs
Synonymous TRP-ML3, TRPML3
Gene
UniProtKB-ID: MCLN3_HUMAN
UniprotKB: Q8TDD5
UniParc: UPI0000073A4B, UPI000013D44C
EMBL: AF475085, AL358789, AK001868
Ensembl: ENSG00000055732
KO: hsa:55283
Nucleutide sequences
EMBL-CDS: AAL84622.1, BAA91951.1
Ensembl_TRS: ENST00000370589, ENST00000341115
Protein sequencees
Ensembl_PRO: ENSP00000359621, ENSP00000342698
RefSeq: NP_001240622.1, NP_060768.8, XP_011540042.1, XP_011540044.1, XP_006710813.1, XP_005271060.1, XP_011540043.1, XP_011540041.2
Others
UniRef100: UniRef100_Q8TDD5
UniRef90: UniRef90_Q8TDD5
UniRef50: UniRef50_Q8TDD5
UniGene: Hs.535239
CCDS: CCDS701.1, CCDS58009.1

全选

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研究热度

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