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55125 CEP192

55125

CEP192

centrosomal protein 192

protein-coding

Homo sapiens

基因描述

Type Description
Definition centrosomal protein 192

研究结论

Date Results Publications
2019-02-09 11:50:00 induced FBXL13 expression downregulates centrosomal gamma-tubulin and disrupts centrosomal microtubule arrays. In addition, depletion of FBXL13 induces high levels of CEP192 and gamma-tubulin at the centrosomes with the consequence of defects in cell motility. 29348145
2018-09-22 10:15:00 Study shows that the interaction between Cep295 and Cep192 seems to be crucial for the integrity of centriole structure and also for daughter-to-mother centriole conversion. 27562453
2017-06-10 11:26:00 Here we demonstrate that CEP192 also recruits the type one protein phosphatase (PP1) via a highly conserved KHVTF docking motif. 28188792
2015-10-31 10:44:00 Interphase cells depleted of Cep192 display significantly higher levels of centrosome-associated Pericentrin while overexpression of Cep192 reduces the levels of centrosomal Pericentrin. 24971877
2015-10-03 10:44:00 Plk1 promotes centrosome-based bipolar spindle formation by forming two functionally nonredundant complexes with Cep192. 26012549

名称对应

Type IDs
Synonymous PPP1R62
Gene
UniProtKB-ID: CE192_HUMAN, Q9HCK3_HUMAN
UniprotKB: Q8TEP8, Q9HCK3
UniParc: UPI0001B09235, UPI00015F45D0, UPI000006CE29, UPI00003FF965
EMBL: AP001357, AB046789, AK074074, AL136818, AF318363, KJ567064, BC144481, AP002449, AK001214
Ensembl: ENSG00000101639
KO: hsa:55125
Nucleutide sequences
EMBL-CDS: AIA61642.1, BAA91559.1, AAL55870.1, AAI44482.1, CAB66752.1, BAB84900.1, BAB13395.1
Gene_ORFName: PP8407
Ensembl_TRS: ENST00000506447
Protein sequencees
Ensembl_PRO: ENSP00000427550
RefSeq: XP_011523977.2, XP_006722390.1, XP_006722389.1, XP_005258164.1, XP_016881295.1, NP_115518.3, XP_016881292.1, XP_016881293.1, XP_024306964.1, XP_011523975.1, XP_024306965.1, XP_016881296.1, XP_005258166.1, XP_006722393.1
Others
UniRef100: UniRef100_Q8TEP8, UniRef100_Q9HCK3
UniRef90: UniRef90_Q8TEP8, UniRef90_Q9HCK3
UniRef50: UniRef50_Q9HCK3, UniRef50_Q8TEP8
UniGene: Hs.100914
CCDS: CCDS32792.2

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