| Type | Description |
|---|---|
| Definition | Lck interacting transmembrane adaptor 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 12:25:00 | Results identified one differentially methylated region associated with cerebral palsy within the transcription start site of the LIME1 gene, which plays a key role in inflammatory pathways. | 29484035 |
| 2012-09-29 11:26:00 | these results establish LIME as a transmembrane adaptor protein linking TCR stimulation to IS formation and integrin activation through activation of Vav(Vav guanine nucleotide exchange factor) | 22395814 |
| Type | IDs |
|---|---|
| Synonymous | LIME, dJ583P15.4 |
| Gene |
UniProtKB-ID:
LIME1_HUMAN,
A0A087WT39_HUMAN
UniprotKB:
Q9H400,
A0A087WT39
UniParc:
UPI000006F9E2,
UPI0004620D4E,
UPI000022F88E
EMBL:
AY203957,
BC017016,
AL121845,
CH471077,
KF510480,
AK000413
Ensembl:
ENSG00000203896
KO:
hsa:54923
|
| Nucleutide sequences |
EMBL-CDS:
EAW75216.1,
AAP34480.1,
EAW75218.1,
EAW75214.1,
EAW75217.1,
EAW75215.1,
BAA91148.1,
EAW75213.1,
AAH17016.1
Gene_ORFName:
LP8067
Ensembl_TRS:
ENST00000309546,
ENST00000480139
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000309521,
ENSP00000477561
RefSeq:
NP_001292583.1,
NP_001292584.1,
NP_060276.2
|
| Others |
UniRef100:
UniRef100_Q9H400,
UniRef100_A0A087WT39
UniRef90:
UniRef90_A0A087WT39,
UniRef90_Q9H400
UniRef50:
UniRef50_Q9H400,
UniRef50_A0A087WT39
UniGene:
Hs.233220
CCDS:
CCDS13536.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 29484035 |
Clin Epigenetics Namitha Mohandas , Sebastian Bass-Stringer , Jovana Maksimovic , Kylie Crompton , Yuk J Loke , Janet Walstab , Susan M Reid , David J Amor , Dinah Reddihough , Jeffrey M Craig |
2018-01-01 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 26186194 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell Edward L Huttlin , Lily Ting , Raphael J Bruckner , Fana Gebreab , Melanie P Gygi , John Szpyt , Stanley Tam , Gabriela Zarraga , Greg Colby , Kurt Baltier , Rui Dong , Virginia Guarani , Laura Pontano Vaites , Alban Ordureau , Ramin Rad , Brian K Erickson , Martin Wühr , Joel Chick , Bo Zhai , Deepak Kolippakkam , Julian Mintseris , Robert A Obar , Tim Harris , Spyros Artavanis-Tsakonas , Mathew E Sowa , Pietro De Camilli , Joao A Paulo , J Wade Harper , Steven P Gygi |
2015-07-16 | - |
| 24870542 |
A draft map of the human proteome. Nature Min-Sik Kim , Sneha M Pinto , Derese Getnet , Raja Sekhar Nirujogi , Srikanth S Manda , Raghothama Chaerkady , Anil K Madugundu , Dhanashree S Kelkar , Ruth Isserlin , Shobhit Jain , Joji K Thomas , Babylakshmi Muthusamy , Pamela Leal-Rojas , Praveen Kumar , Nandini A Sahasrabuddhe , Lavanya Balakrishnan , Jayshree Advani , Bijesh George , Santosh Renuse , Lakshmi Dhevi N Selvan , Arun H Patil , Vishalakshi Nanjappa , Aneesha Radhakrishnan , Samarjeet Prasad , Tejaswini Subbannayya , Rajesh Raju , Manish Kumar , Sreelakshmi K Sreenivasamurthy , Arivusudar Marimuthu , Gajanan J Sathe , Sandip Chavan , Keshava K Datta , Yashwanth Subbannayya , Apeksha Sahu , Soujanya D Yelamanchi , Savita Jayaram , Pavithra Rajagopalan , Jyoti Sharma , Krishna R Murthy , Nazia Syed , Renu Goel , Aafaque A Khan , Sartaj Ahmad , Gourav Dey , Keshav Mudgal , Aditi Chatterjee , Tai-Chung Huang , Jun Zhong , Xinyan Wu , Patrick G Shaw , Donald Freed , Muhammad S Zahari , Kanchan K Mukherjee , Subramanian Shankar , Anita Mahadevan , Henry Lam , Christopher J Mitchell , Susarla Krishna Shankar , Parthasarathy Satishchandra , John T Schroeder , Ravi Sirdeshmukh , Anirban Maitra , Steven D Leach , Charles G Drake , Marc K Halushka , T S Keshava Prasad , Ralph H Hruban , Candace L Kerr , Gary D Bader , Christine A Iacobuzio-Donahue , Harsha Gowda , Akhilesh Pandey |
2014-05-29 | - |
| 23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
| 23128233 |
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature Luke Jostins , Stephan Ripke , Rinse K Weersma , Richard H Duerr , Dermot P McGovern , Ken Y Hui , James C Lee , L Philip Schumm , Yashoda Sharma , Carl A Anderson , Jonah Essers , Mitja Mitrovic , Kaida Ning , Isabelle Cleynen , Emilie Theatre , Sarah L Spain , Soumya Raychaudhuri , Philippe Goyette , Zhi Wei , Clara Abraham , Jean-Paul Achkar , Tariq Ahmad , Leila Amininejad , Ashwin N Ananthakrishnan , Vibeke Andersen , Jane M Andrews , Leonard Baidoo , Tobias Balschun , Peter A Bampton , Alain Bitton , Gabrielle Boucher , Stephan Brand , Carsten Büning , Ariella Cohain , Sven Cichon , Mauro D'Amato , Dirk De Jong , Kathy L Devaney , Marla Dubinsky , Cathryn Edwards , David Ellinghaus , Lynnette R Ferguson , Denis Franchimont , Karin Fransen , Richard Gearry , Michel Georges , Christian Gieger , Jürgen Glas , Talin Haritunians , Ailsa Hart , Chris Hawkey , Matija Hedl , Xinli Hu , Tom H Karlsen , Limas Kupcinskas , Subra Kugathasan , Anna Latiano , Debby Laukens , Ian C Lawrance , Charlie W Lees , Edouard Louis , Gillian Mahy , John Mansfield , Angharad R Morgan , Craig Mowat , William Newman , Orazio Palmieri , Cyriel Y Ponsioen , Uros Potocnik , Natalie J Prescott , Miguel Regueiro , Jerome I Rotter , Richard K Russell , Jeremy D Sanderson , Miquel Sans , Jack Satsangi , Stefan Schreiber , Lisa A Simms , Jurgita Sventoraityte , Stephan R Targan , Kent D Taylor , Mark Tremelling , Hein W Verspaget , Martine De Vos , Cisca Wijmenga , David C Wilson , Juliane Winkelmann , Ramnik J Xavier , Sebastian Zeissig , Bin Zhang , Clarence K Zhang , Hongyu Zhao , International IBD Genetics Consortium (IIBDGC) , Mark S Silverberg , Vito Annese , Hakon Hakonarson , Steven R Brant , Graham Radford-Smith , Christopher G Mathew , John D Rioux , Eric E Schadt , Mark J Daly , Andre Franke , Miles Parkes , Severine Vermeire , Jeffrey C Barrett , Judy H Cho |
2012-11-01 | - |
| 22664934 |
Oncol. Rep. Daniel Böhm , Ksenia Keller , Julia Pieter , Nils Boehm , Dominik Wolters , Wulf Siggelkow , Antje Lebrecht , Marcus Schmidt , Heinz Kölbl , Norbert Pfeiffer , Franz-Hermann Grus |
2012-08-01 |
LOC101060157,
USPL1,
SCGB1D1,
STAG3,
MTHFD2,
POP1,
PRR4,
ELFN2,
MRGPRD,
CLIC1,
LRRK2,
LRIG3,
ZG16B,
COL7A1,
RBBP8NL,
TTBK2,
CST1,
CST2,
TMC8,
CST4,
DDB1,
FREM3,
DLG3,
DMBT1,
KRT78,
ZFC3H1,
SERPINB1,
ENO1,
ENO2,
ENO3,
ABCA3,
ALB,
ALDH3A1,
CEP164,
CNOT1,
SIPA1L3,
PMPCA,
SULF1,
KIAA0556,
MCF2L,
DMXL2,
ZCCHC11,
ALOX5,
KLHL34,
GNL3,
KAT2A,
MDGA1,
GLE1,
PRTG,
LCN1P1,
MRPL18,
GSTP1,
ANXA1,
ANXA2,
ANXA13,
HP,
HSPB1,
APOA1,
KLHL17,
ACTBL2,
IGHA1,
IGHA2,
IGHG2,
IGHG3,
IGHG4,
JCHAIN,
IGKC,
IGLC1,
IGLC2,
MROH7,
KRT1,
KRT9,
TRIM75P,
LCN1,
LCN2,
LCP1,
LGALS3,
LOC400576,
LTF,
LYZ,
MDH1,
MECP2,
SCGB2A1,
MOV10,
LOC439951,
POTEE,
ATP4A,
PRDX1,
PRKAG2,
PDE4C,
PIGR,
PIP,
PRKAG3,
SEMA4C,
LIME1,
WDR60,
NDUFAF7,
ZNF446,
SLF2
|
| 22395814 |
LIME mediates immunological synapse formation through activation of VAV. Mol Cells Myoungsun Son , Inyoung Park , Ok-Hee Lee , Inmoo Rhee , Changwon Park , Yungdae Yun |
2012-04-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员