| Type | Description |
|---|---|
| Definition | dihydrouridine synthase 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 13:12:00 | we establish that while hDus2 dsRBD retains a conventional dsRNA recognition capability, the presence of an N-terminal extension appended to the canonical domain provides additional residues for binding tRNA in a structure-specific mode of action. | 30605527 |
| 2016-04-23 11:54:00 | Here, the X-ray crystal structure of a construct of hDus2 encompassing the catalytic and tRNA-recognition domains (residues 1-340) determined at 1.9 A resolution is presented. | 26143927 |
| 2016-03-05 10:31:00 | This is the first reported case of a tRNA-modifying enzyme (dihydrouridine synthase 2) carrying a dsRNA binding domain used to bind tRNAs. | 26429968 |
| 2012-11-16 08:54:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| 2012-05-12 10:22:00 | crystals belonged to space group P2(1) and contained a single molecule of HsDus2L in the asymmetric unit | 22442237 |
| Type | IDs |
|---|---|
| Synonymous | DUS2L, SMM1, URLC8 |
| Gene |
UniProtKB-ID:
DUS2L_HUMAN,
A0A024R6Z7_HUMAN,
B4DKP8_HUMAN,
E7EUN9_HUMAN
UniprotKB:
Q9NX74,
A0A024R6Z7,
B4DKP8,
E7EUN9
UniParc:
UPI0000036040,
UPI0001AE6836,
UPI00017A7476
EMBL:
CH471092,
AK296663,
AK290578,
AK000406,
AC040162,
AB101210,
AC130462,
BC006527,
KC877614
Ensembl:
ENSG00000167264
KO:
hsa:54920
|
| Nucleutide sequences |
EMBL-CDS:
BAA91143.1,
BAF83267.1,
AAH06527.1,
BAE07219.1,
EAW83207.1,
EAW83208.1,
EAW83209.1,
BAG59260.1
Gene_ORFName:
hCG_28115
Ensembl_TRS:
ENST00000358896,
ENST00000565263,
ENST00000432752
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000351769,
ENSP00000455229,
ENSP00000409498
RefSeq:
NP_060273.1,
NP_001258691.1,
NP_001258692.1
|
| Others |
UniRef100:
UniRef100_Q9NX74,
UniRef100_B4DKP8,
UniRef100_E7EUN9
UniRef90:
UniRef90_Q9NX74,
UniRef90_Q9D7B1
UniRef50:
UniRef50_Q9NX74
UniGene:
Hs.534460,
Hs.744492
CCDS:
CCDS10859.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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