| Type | Description |
|---|---|
| Definition | hematopoietic prostaglandin D synthase |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 11:59:00 | Validation of differentially expressed genes (DEGs) by quantitative RT-PCR showed a significant increase in PLA2 group 4c (Pla2g4c)/COX-2 (Ptgs2)/PGD2 synthase 2 (Hpgds) axis. PGD2 level in bronchoalveolar fluids of the OA-challenged mice was significantly increased. A 24-h incubation of BSM tissues with PGD2 caused a hyperresponsiveness to acetylcholine in naive control mice. | 30161143 |
| 2016-04-23 10:16:00 | H-PGDS deficiency accelerates the production of SDF-1alpha and the activity of MMP-9 in the antigen-stimulated intestine. SDF-1alpha receptor blockade or MMP-9 inhibition relieves the exacerbated mast cell hyperplasia and manifestations observed in H-PGDS(-/-). | 26159556 |
| 2012-07-14 10:33:00 | HPGDS may play a role in the regulation of inflammation and epithelial cell health within the oviduct. | 22374975 |
| 2012-01-28 12:16:00 | Data suggest a role for hematopoietic prostaglandin D synthase-produced prostaglandin D(2) in the initial nuclear translocation of SOX9. | 21887724 |
| 2011-07-02 10:49:00 | These data suggest that PGD(2) generated via HPGDS has detrimental effects after spinal cord injury and that blocking the activity of this enzyme can be beneficial. | 21294159 |
| Type | IDs |
|---|---|
| Synonymous | H-PGDS, Ptgds2 |
| Gene |
UniProtKB-ID:
HPGDS_MOUSE
UniprotKB:
Q9JHF7
UniParc:
UPI0000023348
EMBL:
BC116737,
CH466523,
AB008824,
AK039392,
BC116735,
AK020246,
D82072
Ensembl:
ENSMUSG00000029919
KO:
mmu:54486
|
| Nucleutide sequences |
EMBL-CDS:
AAI16738.1,
BAA97557.1,
BAC30336.1,
BAA96845.1,
BAB32037.1,
EDK98774.1,
AAI16736.1
Ensembl_TRS:
ENSMUST00000031982
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031982
RefSeq:
XP_036008130.1,
XP_036008129.1,
NP_062328.3,
XP_006506461.1
|
| Others |
UniRef100:
UniRef100_Q9JHF7
UniRef90:
UniRef90_O35543
UniRef50:
UniRef50_O35543
UniGene:
Mm.410688
CCDS:
CCDS20205.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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